MRPS12 (mitochondrial ribosomal protein S12)

2009-03-01  

Identity

HGNC
LOCATION
19q13.2
LOCUSID
ALIAS
MPR-S12,MT-RPS12,RPMS12,RPS12,RPSM12

Other Information

Locus ID:

NCBI: 6183
MIM: 603021
HGNC: 10380
Ensembl: ENSG00000128626

Variants:

dbSNP: 6183
ClinVar: 6183
TCGA: ENSG00000128626
COSMIC: MRPS12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000128626ENST00000308018O15235
ENSG00000128626ENST00000308018A0A024R0H2
ENSG00000128626ENST00000402029O15235
ENSG00000128626ENST00000402029A0A024R0H2
ENSG00000128626ENST00000407800O15235
ENSG00000128626ENST00000407800A0A024R0H2

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Pathways

PathwaySourceExternal ID
RibosomeKEGGko03010
RibosomeKEGGhsa03010
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Mitochondrial translationREACTOMER-HSA-5368287
Mitochondrial translation initiationREACTOMER-HSA-5368286
Mitochondrial translation elongationREACTOMER-HSA-5389840
Mitochondrial translation terminationREACTOMER-HSA-5419276

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
187900942008cis-acting sequences and trans-acting factors in the localization of mRNA for mitochondrial ribosomal proteins.16
127061052003Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome.7
194392092009NF-Y influences directionality of transcription from the bidirectional Mrps12/Sarsm promoter in both mouse and human cells.3

Citation

Dessen P

MRPS12 (mitochondrial ribosomal protein S12)

Atlas Genet Cytogenet Oncol Haematol. 2009-03-01

Online version: http://atlasgeneticsoncology.org/gene/50700/mrps12