MRPS16 (mitochondrial ribosomal protein S16)

2014-11-01  

Identity

HGNC
LOCATION
10q22.2
LOCUSID
ALIAS
CGI-132,COXPD2,MRP-S16,RPMS16
FUSION GENES

Other Information

Locus ID:

NCBI: 51021
MIM: 609204
HGNC: 14048
Ensembl: ENSG00000182180

Variants:

dbSNP: 51021
ClinVar: 51021
TCGA: ENSG00000182180
COSMIC: MRPS16

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182180ENST00000372940A6ND22
ENSG00000182180ENST00000372945Q9Y3D3

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Pathways

PathwaySourceExternal ID
RibosomeKEGGko03010
RibosomeKEGGhsa03010
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Mitochondrial translationREACTOMER-HSA-5368287
Mitochondrial translation initiationREACTOMER-HSA-5368286
Mitochondrial translation elongationREACTOMER-HSA-5389840
Mitochondrial translation terminationREACTOMER-HSA-5419276

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.69
155058242004Defective mitochondrial translation caused by a ribosomal protein (MRPS16) mutation.67
185390992008The effect of mutated mitochondrial ribosomal proteins S16 and S22 on the assembly of the small and large ribosomal subunits in human mitochondria.17
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
198070342009[Mutual effect of human ribosomal proteins S5 and S16 on their binding with 18S rRNA fragment 1203-1236/1521-1698].0

Citation

Dessen P

MRPS16 (mitochondrial ribosomal protein S16)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70475/mrps16