MRPS25 (mitochondrial ribosomal protein S25)

2014-11-01  

Identity

HGNC
LOCATION
3p25.1
LOCUSID
ALIAS
COXPD50,MRP-S25,RPMS25
FUSION GENES

Other Information

Locus ID:

NCBI: 64432
MIM: 611987
HGNC: 14511
Ensembl: ENSG00000131368

Variants:

dbSNP: 64432
ClinVar: 64432
TCGA: ENSG00000131368
COSMIC: MRPS25

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000131368ENST00000253686P82663
ENSG00000131368ENST00000420267E7EPW2
ENSG00000131368ENST00000444840P82663
ENSG00000131368ENST00000447299E7EPW2
ENSG00000131368ENST00000449354P82663

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Pathways

PathwaySourceExternal ID
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Mitochondrial translationREACTOMER-HSA-5368287
Mitochondrial translation initiationREACTOMER-HSA-5368286
Mitochondrial translation elongationREACTOMER-HSA-5389840
Mitochondrial translation terminationREACTOMER-HSA-5419276

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
310395822019MRPS25 mutations impair mitochondrial translation and cause encephalomyopathy.2

Citation

Dessen P

MRPS25 (mitochondrial ribosomal protein S25)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70483/mrps25