MRPS27 (mitochondrial ribosomal protein S27)

2017-10-01  

Identity

HGNC
LOCATION
5q13.2
LOCUSID
ALIAS
MRP-S27,S27mt
FUSION GENES

Other Information

Locus ID:

NCBI: 23107
MIM: 611989
HGNC: 14512
Ensembl: ENSG00000113048

Variants:

dbSNP: 23107
ClinVar: 23107
TCGA: ENSG00000113048
COSMIC: MRPS27

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000113048ENST00000261413Q92552
ENSG00000113048ENST00000261413A0A024RAJ1
ENSG00000113048ENST00000457646G5EA06
ENSG00000113048ENST00000508863D6RH20
ENSG00000113048ENST00000513900Q92552
ENSG00000113048ENST00000515404D6RJC7
ENSG00000113048ENST00000522095E5RJ73

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Mitochondrial translationREACTOMER-HSA-5368287
Mitochondrial translation initiationREACTOMER-HSA-5368286
Mitochondrial translation elongationREACTOMER-HSA-5389840
Mitochondrial translation terminationREACTOMER-HSA-5419276

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
228417152012MRPS27 is a pentatricopeptide repeat domain protein required for the translation of mitochondrially encoded proteins.17
287143662017High MRPS23 expression contributes to hepatocellular carcinoma proliferation and indicates poor survival outcomes.3

Citation

Dessen P

MRPS27 (mitochondrial ribosomal protein S27)

Atlas Genet Cytogenet Oncol Haematol. 2017-10-01

Online version: http://atlasgeneticsoncology.org/gene/57220/mrps27