MS4A12 (membrane spanning 4-domains A12)

2010-03-01  

Identity

HGNC
MS4A12
LOCATION
11q12.2
LOCUSID
54860
ALIAS
Ms4a10
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 54860
MIM: 606550
HGNC: 13370
Ensembl: ENSG00000071203

Variants:

dbSNP: 54860
ClinVar: 54860
TCGA: ENSG00000071203
COSMIC: MS4A12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000071203ENST00000016913Q9NXJ0
ENSG00000071203ENST00000526784E9PIX5
ENSG00000071203ENST00000530007E9PNI3
ENSG00000071203ENST00000537076Q9NXJ0

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
184511742008MS4A12 is a colon-selective store-operated calcium channel promoting malignant cell processes.22
197810652009Selective activation of tumor growth-promoting Ca2+ channel MS4A12 in colon cancer by caudal type homeobox transcription factor CDX2.8
278810062017Decreased expression of MS4A12 inhibits differentiation and predicts early stage survival in colon cancer.1

Citation

Dessen P

MS4A12 (membrane spanning 4-domains A12)

Atlas Genet Cytogenet Oncol Haematol. 2010-03-01

Online version: http://atlasgeneticsoncology.org/gene/52808/ms4a12