MSC (musculin)

2008-12-01  

Identity

HGNC
LOCATION
8q13.3
LOCUSID
ALIAS
ABF-1,ABF1,MYOR,bHLHa22
FUSION GENES

Other Information

Locus ID:

NCBI: 9242
MIM: 603628
HGNC: 7321
Ensembl: ENSG00000178860

Variants:

dbSNP: 9242
ClinVar: 9242
TCGA: ENSG00000178860
COSMIC: MSC

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000178860ENST00000325509O60682

Expression (GTEx)

0
50
100
150

References

Pubmed IDYearTitleCitations
150522692004Allele-specific repression of lymphotoxin-alpha by activated B cell factor-1.30
206348912010Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.18
250708432014Transcription factor ABF-1 suppresses plasma cell differentiation but facilitates memory B cell formation.8
286124332017Musculin inhibits human T-helper 17 cell response to interleukin 2 by controlling STAT5B activity.8
183680672008ABF-1 is frequently silenced by promoter methylation in follicular lymphoma, diffuse large B-cell lymphoma and Burkitt's lymphoma.3
311016222019Recurrent MSC E116K mutations in ALK-negative anaplastic large cell lymphoma.2

Citation

Dessen P

MSC (musculin)

Atlas Genet Cytogenet Oncol Haematol. 2008-12-01

Online version: http://atlasgeneticsoncology.org/gene/50561/msc