MSI1 (musashi RNA binding protein 1)

2003-02-01  

Identity

HGNC
LOCATION
12q24.31
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 4440
MIM: 603328
HGNC: 7330
Ensembl: ENSG00000135097

Variants:

dbSNP: 4440
ClinVar: 4440
TCGA: ENSG00000135097
COSMIC: MSI1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000135097ENST00000257552O43347
ENSG00000135097ENST00000546985H0YHB7

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
mRNA surveillance pathwayKEGGko03015
mRNA surveillance pathwayKEGGhsa03015

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
162143662006The RNA-binding protein Musashi-1 regulates neural development through the translational repression of p21WAF-1.76
184715192008Knockdown of RNA binding protein musashi-1 leads to tumor regression in vivo.71
184733322008Increased expression of the adult stem cell marker Musashi-1 in endometriosis and endometrial carcinoma.58
207272042010Musashi1 regulates breast tumor cell proliferation and is a prognostic indicator of poor survival.55
184198302008Stem-cell-abundant proteins Nanog, Nucleostemin and Musashi1 are highly expressed in malignant cervical epithelial cells.50
218292012011Sequential expression of putative stem cell markers in gastric carcinogenesis.44
285724542017Neurodevelopmental protein Musashi-1 interacts with the Zika genome and promotes viral replication.44
272812082016Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma.41
281438722017Musashi RNA-Binding Proteins as Cancer Drivers and Novel Therapeutic Targets.41
192583082009Genomic analyses of musashi1 downstream targets show a strong association with cancer-related processes.38

Citation

Dessen P

MSI1 (musashi RNA binding protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41432/msi1