MSRB1 (methionine sulfoxide reductase B1)

2005-02-01  

Identity

HGNC
LOCATION
16p13.3
LOCUSID
ALIAS
HSPC270,SELENOR,SELENOX,SELR,SELX,SEPX1,SepR

Other Information

Locus ID:

NCBI: 51734
MIM: 606216
HGNC: 14133
Ensembl: ENSG00000198736

Variants:

dbSNP: 51734
ClinVar: 51734
TCGA: ENSG00000198736
COSMIC: MSRB1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198736ENST00000361871Q9NZV6
ENSG00000198736ENST00000399753A8MYR2
ENSG00000198736ENST00000473663H3BTT6
ENSG00000198736ENST00000564908H3BS64
ENSG00000198736ENST00000622125A0A087WXE3

Expression (GTEx)

0
50
100
150
200
250
300
350
400

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Protein repairREACTOMER-HSA-5676934

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
360847912022The selenoprotein methionine sulfoxide reductase B1 (MSRB1).16
360847912022The selenoprotein methionine sulfoxide reductase B1 (MSRB1).16
293950812018Methionine sulfoxide reductase B1 regulates proliferation and invasion by affecting mitogen-activated protein kinase pathway and epithelial-mesenchymal transition in u2os cells.4
293950812018Methionine sulfoxide reductase B1 regulates proliferation and invasion by affecting mitogen-activated protein kinase pathway and epithelial-mesenchymal transition in u2os cells.4
268759812016Selenoprotein R Protects Human Lens Epithelial Cells against D-Galactose-Induced Apoptosis by Regulating Oxidative Stress and Endoplasmic Reticulum Stress.11
268993212016Selenoprotein X Gene Knockdown Aggravated H2O2-Induced Apoptosis in Liver LO2 Cells.5
268759812016Selenoprotein R Protects Human Lens Epithelial Cells against D-Galactose-Induced Apoptosis by Regulating Oxidative Stress and Endoplasmic Reticulum Stress.11
268993212016Selenoprotein X Gene Knockdown Aggravated H2O2-Induced Apoptosis in Liver LO2 Cells.5
243426072014Effect of methionine sulfoxide reductase B1 (SelR) gene silencing on peroxynitrite-induced F-actin disruption in human lens epithelial cells.6
243426072014Effect of methionine sulfoxide reductase B1 (SelR) gene silencing on peroxynitrite-induced F-actin disruption in human lens epithelial cells.6
232709452013Effect of methionine sulfoxide reductase B1 silencing on high-glucose-induced apoptosis of human lens epithelial cells.7
238052182013Direct Interaction of Selenoprotein R with Clusterin and Its Possible Role in Alzheimer's Disease.9
239887882013Proteome alteration in oxidative stress-sensitive methionine sulfoxide reductase-silenced HEK293 cells.7
232709452013Effect of methionine sulfoxide reductase B1 silencing on high-glucose-induced apoptosis of human lens epithelial cells.7
238052182013Direct Interaction of Selenoprotein R with Clusterin and Its Possible Role in Alzheimer's Disease.9

Citation

Dessen P

MSRB1 (methionine sulfoxide reductase B1)

Atlas Genet Cytogenet Oncol Haematol. 2005-02-01

Online version: http://atlasgeneticsoncology.org/gene/43014/msrb1