MT1E (metallothionein 1E)

2009-08-01  

Identity

HGNC
LOCATION
16q13
LOCUSID
ALIAS
MT-1E,MT-IE,MT1,MTD

Other Information

Locus ID:

NCBI: 4493
MIM: 156351
HGNC: 7397
Ensembl: ENSG00000169715

Variants:

dbSNP: 4493
ClinVar: 4493
TCGA: ENSG00000169715
COSMIC: MT1E

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169715ENST00000306061P04732
ENSG00000169715ENST00000330439P04732
ENSG00000169715ENST00000568293H3BU80

Expression (GTEx)

0
100
200
300
400
500
600
700

Pathways

PathwaySourceExternal ID
Mineral absorptionKEGGko04978
Mineral absorptionKEGGhsa04978
MetabolismREACTOMER-HSA-1430728
Response to metal ionsREACTOMER-HSA-5660526
Metallothioneins bind metalsREACTOMER-HSA-5661231

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
187243902008Overlapping gene expression profiles of cell migration and tumor invasion in human bladder cancer identify metallothionein 1E and nicotinamide N-methyltransferase as novel regulators of cell migration.50
183491102008Polymorphisms in metallothionein-1 and -2 genes associated with the risk of type 2 diabetes mellitus and its complications.20
228430662012Role of metallothionein 1E in the migration and invasion of human glioma cell lines.17
205512112010Increased metallothionein gene expression, zinc, and zinc-dependent resistance to apoptosis in circulating monocytes during HIV viremia.16
208487332010Metallothionein 1E is methylated in malignant melanoma and increases sensitivity to cisplatin-induced apoptosis.14
194209862009Epigenetic alteration of the metallothionein 1E gene in human endometrial carcinomas.7
285381722017Using hESCs to Probe the Interaction of the Diabetes-Associated Genes CDKAL1 and MT1E.7
157477762003Dose-dependent transcriptome changes by metal ores on a human acute lymphoblastic leukemia cell line.3
213585522011Profile of adipose tissue gene expression in premenopausal and postmenopausal women: site-specific differences.1
310023542019DNA methylation of metallothionein genes is associated with the clinical features of renal cell carcinoma.0

Citation

Dessen P

MT1E (metallothionein 1E)

Atlas Genet Cytogenet Oncol Haematol. 2009-08-01

Online version: http://atlasgeneticsoncology.org/gene/50997/mt1e