MT1F (metallothionein 1F)

2007-02-01  

Identity

HGNC
LOCATION
16q13
LOCUSID
ALIAS
MT1
FUSION GENES

Other Information

Locus ID:

NCBI: 4494
MIM: 156352
HGNC: 7398
Ensembl: ENSG00000198417

Variants:

dbSNP: 4494
ClinVar: 4494
TCGA: ENSG00000198417
COSMIC: MT1F

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198417ENST00000334350P04733
ENSG00000198417ENST00000568475H3BRY8

Expression (GTEx)

0
50
100
150
200
250
300

Pathways

PathwaySourceExternal ID
Mineral absorptionKEGGko04978
Mineral absorptionKEGGhsa04978
MetabolismREACTOMER-HSA-1430728
Response to metal ionsREACTOMER-HSA-5660526
Metallothioneins bind metalsREACTOMER-HSA-5661231

References

Pubmed IDYearTitleCitations
214092062011The "magic numbers" of metallothionein.33
235369592013Zinc protects against diabetes-induced pathogenic changes in the aorta: roles of metallothionein and nuclear factor (erythroid-derived 2)-like 2.24
224260382012Downregulation of metallothionein 1F, a putative oncosuppressor, by loss of heterozygosity in colon cancer tissue.17
218201542012Metallothionein expression in colorectal cancer: relevance of different isoforms for tumor progression and patient survival.16
230640512013Metallothionein 1F and 2A overexpression predicts poor outcome of non-small cell lung cancer patients.14
192519482009Fine ambient particles induce oxidative stress and metal binding genes in human alveolar macrophages.10
211280012011Metallothionein-1 genotypes in the risk of oral squamous cell carcinoma.10
153696322003The relationship between metallothionein-1F (MT1F) gene and hepatocellular carcinoma.8
244404672014Significance of the rapid increase in GSH levels in the protective response to cadmium exposure through phosphorylated Nrf2 signaling in Jurkat T-cells.4
208129682010Modulation of metallothionein isoforms is associated with collagen deposition in proliferating keloid fibroblasts in vitro.3

Citation

Dessen P

MT1F (metallothionein 1F)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45639/mt1f