MT2A (metallothionein 2A)

2003-08-01  

Identity

HGNC
LOCATION
16q13
LOCUSID
ALIAS
MT-2,MT-II,MT2
FUSION GENES

Other Information

Locus ID:

NCBI: 4502
MIM: 156360
HGNC: 7406
Ensembl: ENSG00000125148

Variants:

dbSNP: 4502
ClinVar: 4502
TCGA: ENSG00000125148
COSMIC: MT2A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000125148ENST00000245185P02795
ENSG00000125148ENST00000561491H3BSP9

Expression (GTEx)

0
500
1000
1500
2000
2500
3000
3500
4000

Pathways

PathwaySourceExternal ID
Mineral absorptionKEGGko04978
Mineral absorptionKEGGhsa04978
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Interferon SignalingREACTOMER-HSA-913531
Interferon gamma signalingREACTOMER-HSA-877300
MetabolismREACTOMER-HSA-1430728
Response to metal ionsREACTOMER-HSA-5660526
Metallothioneins bind metalsREACTOMER-HSA-5661231

References

Pubmed IDYearTitleCitations
366494422023Esterase D interacts with metallothionein 2A and inhibits the migration of A549 lung cancer cells in vitro.0
366906792023Association of metallothionein 2A rs10636 with low mean corpuscular volume (MCV), low mean corpuscular haemoglobin (MCH) in healthy Taiwanese.1
369810432023An Assessment of MT1A (rs11076161), MT2A (rs28366003) and MT1L (rs10636) Gene Polymorphisms and MT2 Concentration in Women with Endometrial Pathologies.0
377131312023Single-cell transcriptome analysis revealing the intratumoral heterogeneity of ccRCC and validation of MT2A in pathogenesis.9
366494422023Esterase D interacts with metallothionein 2A and inhibits the migration of A549 lung cancer cells in vitro.0
366906792023Association of metallothionein 2A rs10636 with low mean corpuscular volume (MCV), low mean corpuscular haemoglobin (MCH) in healthy Taiwanese.1
369810432023An Assessment of MT1A (rs11076161), MT2A (rs28366003) and MT1L (rs10636) Gene Polymorphisms and MT2 Concentration in Women with Endometrial Pathologies.0
377131312023Single-cell transcriptome analysis revealing the intratumoral heterogeneity of ccRCC and validation of MT2A in pathogenesis.9
350751272022Structural basis of the ligand binding and signaling mechanism of melatonin receptors.13
351077382022Downregulation of metallothionein 2A reduces migration, invasion and proliferation activities in human squamous cell carcinoma cells.2
360605202022ptk2 and mt2a Genes Expression in Gastritis and Gastric Cancer Patients with Helicobacter pylori Infection.1
350751272022Structural basis of the ligand binding and signaling mechanism of melatonin receptors.13
351077382022Downregulation of metallothionein 2A reduces migration, invasion and proliferation activities in human squamous cell carcinoma cells.2
360605202022ptk2 and mt2a Genes Expression in Gastritis and Gastric Cancer Patients with Helicobacter pylori Infection.1
330849772021Expression profiles of metallothionein-I/II and megalin/LRP-2 in uterine cervical squamous lesions.3

Citation

Dessen P

MT2A (metallothionein 2A)

Atlas Genet Cytogenet Oncol Haematol. 2003-08-01

Online version: http://atlasgeneticsoncology.org/gene/41441/mt2a