Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 27085
MIM: 605927
HGNC: 7417
Ensembl: ENSG00000172167
Variants:
dbSNP: 27085
ClinVar: 27085
TCGA: ENSG00000172167
COSMIC: MTBP
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000172167 | ENST00000305949 | Q96DY7 |
| ENSG00000172167 | ENST00000519556 | H0YB28 |
| ENSG00000172167 | ENST00000523373 | Q96DY7 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32966791 | 2020 | Binding of the Treslin-MTBP Complex to Specific Regions of the Human Genome Promotes the Initiation of DNA Replication. | 12 |
| 32966791 | 2020 | Binding of the Treslin-MTBP Complex to Specific Regions of the Human Genome Promotes the Initiation of DNA Replication. | 12 |
| 25759210 | 2015 | MTBP inhibits migration and metastasis of hepatocellular carcinoma. | 16 |
| 26280083 | 2015 | MTBP Promotes the Invasion and Metastasis of Hepatocellular Carcinoma by Enhancing the MDM2-Mediated Degradation of E-Cadherin. | 11 |
| 25759210 | 2015 | MTBP inhibits migration and metastasis of hepatocellular carcinoma. | 16 |
| 26280083 | 2015 | MTBP Promotes the Invasion and Metastasis of Hepatocellular Carcinoma by Enhancing the MDM2-Mediated Degradation of E-Cadherin. | 11 |
| 24786788 | 2014 | Oncogenic protein MTBP interacts with MYC to promote tumorigenesis. | 31 |
| 24866769 | 2014 | MTBP is overexpressed in triple-negative breast cancer and contributes to its growth and survival. | 23 |
| 24786788 | 2014 | Oncogenic protein MTBP interacts with MYC to promote tumorigenesis. | 31 |
| 24866769 | 2014 | MTBP is overexpressed in triple-negative breast cancer and contributes to its growth and survival. | 23 |
| 22370640 | 2013 | MTBP suppresses cell migration and filopodia formation by inhibiting ACTN4. | 37 |
| 23704573 | 2013 | Identification of a heteromeric complex that promotes DNA replication origin firing in human cells. | 51 |
| 22370640 | 2013 | MTBP suppresses cell migration and filopodia formation by inhibiting ACTN4. | 37 |
| 23704573 | 2013 | Identification of a heteromeric complex that promotes DNA replication origin firing in human cells. | 51 |
| 21274008 | 2011 | MTBP plays a crucial role in mitotic progression and chromosome segregation. | 14 |
Citation
Dessen P
MTBP (MDM2 binding protein)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41447/mtbp
