Identity
HGNC
LOCATION
8q22.1
LOCUSID
ALIAS
3D3,AEG-1,AEG1,LYRIC,LYRIC/3D3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 92140
MIM: 610323
HGNC: 29608
Ensembl: ENSG00000147649
Variants:
dbSNP: 92140
ClinVar: 92140
TCGA: ENSG00000147649
COSMIC: MTDH
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37695492 | 2024 | Linc00239 Promotes Colorectal Cancer Development via MicroRNA-182-5p/Metadherin Axis. | 0 |
| 37995969 | 2024 | Metadherin orchestrates PKA and PKM2 to activate β-catenin signaling in podocytes during proteinuric chronic kidney disease. | 1 |
| 38093418 | 2024 | Metadherin inhibits chemosensitivity of triple-negative breast cancer to paclitaxel via activation of AKT/GSK-3β signaling pathway. | 0 |
| 38516242 | 2024 | Metadherin promotes stem cell phenotypes and correlated with immune infiltration in hepatocellular carcinoma. | 1 |
| 38578957 | 2024 | HIV-1 gp120 amplifies astrocyte elevated gene-1 activity to compromise the integrity of the outer blood-retinal barrier. | 0 |
| 38615202 | 2024 | Plasma metadherin mRNA expression in bladder cancer. | 0 |
| 38625581 | 2024 | USP7 promotes cervical cancer progression by stabilizing MTDH expression through deubiquitination. | 0 |
| 37695492 | 2024 | Linc00239 Promotes Colorectal Cancer Development via MicroRNA-182-5p/Metadherin Axis. | 0 |
| 37995969 | 2024 | Metadherin orchestrates PKA and PKM2 to activate β-catenin signaling in podocytes during proteinuric chronic kidney disease. | 1 |
| 38093418 | 2024 | Metadherin inhibits chemosensitivity of triple-negative breast cancer to paclitaxel via activation of AKT/GSK-3β signaling pathway. | 0 |
| 38516242 | 2024 | Metadherin promotes stem cell phenotypes and correlated with immune infiltration in hepatocellular carcinoma. | 1 |
| 38578957 | 2024 | HIV-1 gp120 amplifies astrocyte elevated gene-1 activity to compromise the integrity of the outer blood-retinal barrier. | 0 |
| 38615202 | 2024 | Plasma metadherin mRNA expression in bladder cancer. | 0 |
| 38625581 | 2024 | USP7 promotes cervical cancer progression by stabilizing MTDH expression through deubiquitination. | 0 |
| 36385375 | 2023 | MTDH-stabilized DDX17 promotes tumor initiation and progression through interacting with YB1 to induce EGFR transcription in Hepatocellular Carcinoma. | 4 |
Citation
Dessen P
MTDH (metadherin)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43863/mtdh
