MTF2 (metal response element binding transcription factor 2)

2014-08-01  

Identity

HGNC
LOCATION
1p22.1
LOCUSID
ALIAS
M96,PCL2,TDRD19A,dJ976O13.2
FUSION GENES

Other Information

Locus ID:

NCBI: 22823
MIM: 609882
HGNC: 29535
Ensembl: ENSG00000143033

Variants:

dbSNP: 22823
ClinVar: 22823
TCGA: ENSG00000143033
COSMIC: MTF2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143033ENST00000370298Q9Y483
ENSG00000143033ENST00000370303Q9Y483
ENSG00000143033ENST00000540243Q9Y483
ENSG00000143033ENST00000540243B4DZG1
ENSG00000143033ENST00000545708Q9Y483
ENSG00000143033ENST00000545708B4DZG1

Expression (GTEx)

0
5
10
15
20
25
30
35

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Epigenetic regulation of gene expressionREACTOMER-HSA-212165
PRC2 methylates histones and DNAREACTOMER-HSA-212300

References

Pubmed IDYearTitleCitations
259235372015An aromatic cage is required but not sufficient for binding of Tudor domains of the Polycomblike protein family to H3K36me3.3
301157032018Targeting the MTF2-MDM2 Axis Sensitizes Refractory Acute Myeloid Leukemia to Chemotherapy.3

Citation

Dessen P

MTF2 (metal response element binding transcription factor 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54476/mtf2