MTFP1 (mitochondrial fission process 1)

2014-11-01 Affiliation

Identity

HGNC

MTFP1

LOCATION

22q12.2

LOCUSID

51537

ALIAS

HSPC242,MTP18

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 51537
MIM: 610235
HGNC: 26945
Ensembl: ENSG00000242114

Variants:

dbSNP: 51537
ClinVar: 51537
TCGA: ENSG00000242114
COSMIC: MTFP1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000242114	ENST00000266263	Q9UDX5
ENSG00000242114	ENST00000266263	A0A024R1E4
ENSG00000242114	ENST00000355143	Q9UDX5
ENSG00000242114	ENST00000407550	B5MC22
ENSG00000242114	ENST00000412752	F8WEN7
ENSG00000242114	ENST00000629597	F8WEN7

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
15155745	2004	Knockdown of MTP18, a novel phosphatidylinositol 3-kinase-dependent protein, affects mitochondrial morphology and induces apoptosis.	35
19878569	2009	Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of coronary atherosclerosis.	28
18660489	2008	Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.	26
30325740	2018	MicroRNA-668 represses MTP18 to preserve mitochondrial dynamics in ischemic acute kidney injury.	18
20877624	2010	Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.	17
19578796	2009	Association of genetic variants with chronic kidney disease in individuals with different lipid profiles.	7

Citation

Dessen P

MTFP1 (mitochondrial fission process 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70541/mtfp1