Atlas of Genetics and Cytogenetics in Oncology and Haematology

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MTG2 (mitochondrial ribosome associated GTPase 2)

Identity

Alias_namesGTPBP5
GTP-binding protein 5 (putative)
GTP binding protein 5 (putative)
mitochondrial ribosome-associated GTPase 2
Alias_symbol (synonym)FLJ10741
dJ1005F21.2
ObgH1
Other alias
HGNC (Hugo) MTG2
LocusID (NCBI) 26164
Atlas_Id 70546
Location 20q13.33  [Link to chromosome band 20q13]
Location_base_pair Starts at 62183025 and ends at 62202754 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LRRCC1 (8q21.2) / MTG2 (20q13.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)MTG2   16239
Cards
Entrez_Gene (NCBI)MTG2  26164  mitochondrial ribosome associated GTPase 2
AliasesGTPBP5; ObgH1; dJ1005F21.2
GeneCards (Weizmann)MTG2
Ensembl hg19 (Hinxton)ENSG00000101181 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101181 [Gene_View]  ENSG00000101181 [Sequence]  chr20:62183025-62202754 [Contig_View]  MTG2 [Vega]
ICGC DataPortalENSG00000101181
TCGA cBioPortalMTG2
AceView (NCBI)MTG2
Genatlas (Paris)MTG2
WikiGenes26164
SOURCE (Princeton)MTG2
Genetics Home Reference (NIH)MTG2
Genomic and cartography
GoldenPath hg38 (UCSC)MTG2  -     chr20:62183025-62202754 +  20q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MTG2  -     20q13.33   [Description]    (hg19-Feb_2009)
GoldenPathMTG2 - 20q13.33 [CytoView hg19]  MTG2 - 20q13.33 [CytoView hg38]
ImmunoBaseENSG00000101181
Mapping of homologs : NCBIMTG2 [Mapview hg19]  MTG2 [Mapview hg38]
OMIM610919   
Gene and transcription
Genbank (Entrez)AK001603 AK124572 AK299147 AK299189 AK299726
RefSeq transcript (Entrez)NM_015666
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MTG2
Cluster EST : UnigeneHs.340636 [ NCBI ]
CGAP (NCI)Hs.340636
Alternative Splicing GalleryENSG00000101181
Gene ExpressionMTG2 [ NCBI-GEO ]   MTG2 [ EBI - ARRAY_EXPRESS ]   MTG2 [ SEEK ]   MTG2 [ MEM ]
Gene Expression Viewer (FireBrowse)MTG2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26164
GTEX Portal (Tissue expression)MTG2
Human Protein AtlasENSG00000101181-MTG2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H4K7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H4K7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H4K7
Splice isoforms : SwissVarQ9H4K7
PhosPhoSitePlusQ9H4K7
Domaine pattern : Prosite (Expaxy)G_OBG (PS51710)   
Domains : Interpro (EBI)G_OBG    GTP-bd_Obg    GTP-bd_Obg/CgtA    GTP1_OBG_dom    GTP1_OBG_dom_sf    GTP_binding_domain    P-loop_NTPase    Small_GTP-bd_dom   
Domain families : Pfam (Sanger)GTP1_OBG (PF01018)    MMR_HSR1 (PF01926)   
Domain families : Pfam (NCBI)pfam01018    pfam01926   
Conserved Domain (NCBI)MTG2
DMDM Disease mutations26164
Blocks (Seattle)MTG2
SuperfamilyQ9H4K7
Human Protein Atlas [tissue]ENSG00000101181-MTG2 [tissue]
Peptide AtlasQ9H4K7
HPRD13617
IPIIPI00878209   IPI01013338   IPI00908433   IPI00646906   IPI00745132   
Protein Interaction databases
DIP (DOE-UCLA)Q9H4K7
IntAct (EBI)Q9H4K7
FunCoupENSG00000101181
BioGRIDMTG2
STRING (EMBL)MTG2
ZODIACMTG2
Ontologies - Pathways
QuickGOQ9H4K7
Ontology : AmiGOmagnesium ion binding  GTPase activity  GTP binding  mitochondrial inner membrane  mitochondrial matrix  mitochondrial ribosome  ribosome biogenesis  regulation of respiratory system process  regulation of mitochondrial translation  
Ontology : EGO-EBImagnesium ion binding  GTPase activity  GTP binding  mitochondrial inner membrane  mitochondrial matrix  mitochondrial ribosome  ribosome biogenesis  regulation of respiratory system process  regulation of mitochondrial translation  
NDEx NetworkMTG2
Atlas of Cancer Signalling NetworkMTG2
Wikipedia pathwaysMTG2
Orthology - Evolution
OrthoDB26164
GeneTree (enSembl)ENSG00000101181
Phylogenetic Trees/Animal Genes : TreeFamMTG2
HOGENOMQ9H4K7
Homologs : HomoloGeneMTG2
Homology/Alignments : Family Browser (UCSC)MTG2
Gene fusions - Rearrangements
Fusion : QuiverMTG2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMTG2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MTG2
dbVarMTG2
ClinVarMTG2
1000_GenomesMTG2 
Exome Variant ServerMTG2
ExAC (Exome Aggregation Consortium)ENSG00000101181
GNOMAD BrowserENSG00000101181
Varsome BrowserMTG2
Genetic variants : HAPMAP26164
Genomic Variants (DGV)MTG2 [DGVbeta]
DECIPHERMTG2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMTG2 
Mutations
ICGC Data PortalMTG2 
TCGA Data PortalMTG2 
Broad Tumor PortalMTG2
OASIS PortalMTG2 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDMTG2
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch MTG2
DgiDB (Drug Gene Interaction Database)MTG2
DoCM (Curated mutations)MTG2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MTG2 (select a term)
intoGenMTG2
Cancer3DMTG2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610919   
Orphanet
DisGeNETMTG2
MedgenMTG2
Genetic Testing Registry MTG2
NextProtQ9H4K7 [Medical]
TSGene26164
GENETestsMTG2
Target ValidationMTG2
Huge Navigator MTG2 [HugePedia]
snp3D : Map Gene to Disease26164
BioCentury BCIQMTG2
ClinGenMTG2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26164
Chemical/Pharm GKB GenePA29059
Clinical trialMTG2
Miscellaneous
canSAR (ICR)MTG2 (select the gene name)
DataMed IndexMTG2
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMTG2
EVEXMTG2
GoPubMedMTG2
iHOPMTG2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Sep 3 15:57:00 CEST 2019
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