MTG2 (mitochondrial ribosome associated GTPase 2)

2014-11-01  

Identity

HGNC
LOCATION
20q13.33
LOCUSID
ALIAS
GTPBP5,ObgH1,dJ1005F21.2
FUSION GENES

Other Information

Locus ID:

NCBI: 26164
MIM: 610919
HGNC: 16239
Ensembl: ENSG00000101181

Variants:

dbSNP: 26164
ClinVar: 26164
TCGA: ENSG00000101181
COSMIC: MTG2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000101181ENST00000370823Q9H4K7
ENSG00000101181ENST00000448254Q5JXJ0
ENSG00000101181ENST00000467101B4DRC1

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
233964482013Human G-proteins, ObgH1 and Mtg1, associate with the large mitochondrial ribosome subunit and are involved in translation and assembly of respiratory complexes.20
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
170547262006Human small G proteins, ObgH1, and ObgH2, participate in the maintenance of mitochondria and nucleolar architectures.13
216081042011De novo deletion of chromosome 20q13.33 in a patient with tracheo-esophageal fistula, cardiac defects and genitourinary anomalies implicates GTPBP5 as a candidate gene.8

Citation

Dessen P

MTG2 (mitochondrial ribosome associated GTPase 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70546/mtg2