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MTSS2 (MTSS I-BAR domain containing 2)

Identity

Other aliasABBA
ABBA-1
ABBA1
MTSS1L
HGNC (Hugo) MTSS2
LocusID (NCBI) 92154
Atlas_Id 50535
Location 16q22.1  [Link to chromosome band 16q22]
Location_base_pair Starts at 70661204 and ends at 70686053 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MTSS1L 16q22.1 / VAC14 16q22.1
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute



Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  MTSS1L/VAC14 (16q22)


External links

Nomenclature
HGNC (Hugo)MTSS2   25094
Cards
Entrez_Gene (NCBI)MTSS2  92154  MTSS I-BAR domain containing 2
AliasesABBA; ABBA-1; ABBA1; MTSS1L
GeneCards (Weizmann)MTSS2
Ensembl hg19 (Hinxton)ENSG00000132613 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000132613 [Gene_View]  ENSG00000132613 [Sequence]  chr16:70661204-70686053 [Contig_View]  MTSS2 [Vega]
ICGC DataPortalENSG00000132613
TCGA cBioPortalMTSS2
AceView (NCBI)MTSS2
Genatlas (Paris)MTSS2
WikiGenes92154
SOURCE (Princeton)MTSS2
Genetics Home Reference (NIH)MTSS2
Genomic and cartography
GoldenPath hg38 (UCSC)MTSS2  -     chr16:70661204-70686053 -  -   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MTSS2  -     -   [Description]    (hg19-Feb_2009)
GoldenPathMTSS2 - - [CytoView hg19]  MTSS2 - - [CytoView hg38]
ImmunoBaseENSG00000132613
genome Data Viewer NCBIMTSS2 [Mapview hg19]  
OMIM616951   
Gene and transcription
Genbank (Entrez)AB115770 BC002770 BC011452 BC024752 BC025271
RefSeq transcript (Entrez)NM_138383
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MTSS2
Alternative Splicing GalleryENSG00000132613
Gene ExpressionMTSS2 [ NCBI-GEO ]   MTSS2 [ EBI - ARRAY_EXPRESS ]   MTSS2 [ SEEK ]   MTSS2 [ MEM ]
Gene Expression Viewer (FireBrowse)MTSS2 [ Firebrowse - Broad ]
GenevisibleExpression of MTSS2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)92154
GTEX Portal (Tissue expression)MTSS2
Human Protein AtlasENSG00000132613-MTSS2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ765P7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ765P7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ765P7
Splice isoforms : SwissVarQ765P7
PhosPhoSitePlusQ765P7
Domaine pattern : Prosite (Expaxy)IMD (PS51338)   
Domains : Interpro (EBI)AH/BAR_dom_sf    I-BAR_dom    MTSS1/MTSS2    MTSS2   
Domain families : Pfam (Sanger)IMD (PF08397)   
Domain families : Pfam (NCBI)pfam08397   
Conserved Domain (NCBI)MTSS2
DMDM Disease mutations92154
Blocks (Seattle)MTSS2
SuperfamilyQ765P7
Human Protein Atlas [tissue]ENSG00000132613-MTSS2 [tissue]
Peptide AtlasQ765P7
HPRD14289
Protein Interaction databases
DIP (DOE-UCLA)Q765P7
IntAct (EBI)Q765P7
FunCoupENSG00000132613
BioGRIDMTSS2
STRING (EMBL)MTSS2
ZODIACMTSS2
Ontologies - Pathways
QuickGOQ765P7
Ontology : AmiGOactin monomer binding  GTPase activator activity  phosphatidylinositol-4,5-bisphosphate binding  plasma membrane organization  lamellipodium  cortical actin cytoskeleton  ruffle membrane  cellular response to platelet-derived growth factor stimulus  Rac GTPase binding  activation of GTPase activity  ruffle assembly  lamellipodium organization  
Ontology : EGO-EBIactin monomer binding  GTPase activator activity  phosphatidylinositol-4,5-bisphosphate binding  plasma membrane organization  lamellipodium  cortical actin cytoskeleton  ruffle membrane  cellular response to platelet-derived growth factor stimulus  Rac GTPase binding  activation of GTPase activity  ruffle assembly  lamellipodium organization  
NDEx NetworkMTSS2
Atlas of Cancer Signalling NetworkMTSS2
Wikipedia pathwaysMTSS2
Orthology - Evolution
OrthoDB92154
GeneTree (enSembl)ENSG00000132613
Phylogenetic Trees/Animal Genes : TreeFamMTSS2
HOGENOMQ765P7
Homologs : HomoloGeneMTSS2
Homology/Alignments : Family Browser (UCSC)MTSS2
Gene fusions - Rearrangements
Fusion : MitelmanMTSS1L/VAC14 [16q22.1/16q22.1]  
Fusion PortalMTSS1L 16q22.1 VAC14 16q22.1 LUSC
Fusion : QuiverMTSS2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMTSS2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MTSS2
dbVarMTSS2
ClinVarMTSS2
1000_GenomesMTSS2 
Exome Variant ServerMTSS2
GNOMAD BrowserENSG00000132613
Varsome BrowserMTSS2
Genetic variants : HAPMAP92154
Genomic Variants (DGV)MTSS2 [DGVbeta]
DECIPHERMTSS2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMTSS2 
Mutations
ICGC Data PortalMTSS2 
TCGA Data PortalMTSS2 
Broad Tumor PortalMTSS2
OASIS PortalMTSS2 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDMTSS2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MTSS2
DgiDB (Drug Gene Interaction Database)MTSS2
DoCM (Curated mutations)MTSS2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MTSS2 (select a term)
intoGenMTSS2
Cancer3DMTSS2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616951   
Orphanet
DisGeNETMTSS2
MedgenMTSS2
Genetic Testing Registry MTSS2
NextProtQ765P7 [Medical]
TSGene92154
GENETestsMTSS2
Target ValidationMTSS2
Huge Navigator MTSS2 [HugePedia]
snp3D : Map Gene to Disease92154
BioCentury BCIQMTSS2
ClinGenMTSS2
Clinical trials, drugs, therapy
Protein Interactions : CTD92154
Pharm GKB GenePA164723215
Clinical trialMTSS2
Miscellaneous
canSAR (ICR)MTSS2 (select the gene name)
HarmonizomeMTSS2
DataMed IndexMTSS2
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMTSS2
EVEXMTSS2
GoPubMedMTSS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jul 10 19:30:42 CEST 2020

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