MUC12 (mucin 12, cell surface associated)

2014-11-01  

Identity

HGNC
LOCATION
7q22.1
LOCUSID
ALIAS
MUC-11,MUC-12,MUC11
FUSION GENES

Other Information

Locus ID:

NCBI: 10071
MIM: 604609
HGNC: 7510
Ensembl: ENSG00000205277

Variants:

dbSNP: 10071
ClinVar: 10071
TCGA: ENSG00000205277
COSMIC: MUC12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000205277ENST00000305119H7BXN1
ENSG00000205277ENST00000379442Q9UKN1
ENSG00000205277ENST00000536621Q9UKN1

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
O-linked glycosylationREACTOMER-HSA-5173105
O-linked glycosylation of mucinsREACTOMER-HSA-913709
Termination of O-glycan biosynthesisREACTOMER-HSA-977068
DiseaseREACTOMER-HSA-1643685
Diseases of glycosylationREACTOMER-HSA-3781865
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
C-type lectin receptors (CLRs)REACTOMER-HSA-5621481
Dectin-2 familyREACTOMER-HSA-5621480
Diseases associated with O-glycosylation of proteinsREACTOMER-HSA-3906995
Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)REACTOMER-HSA-5083632
Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)REACTOMER-HSA-5083625
Defective GALNT12 causes colorectal cancer 1 (CRCS1)REACTOMER-HSA-5083636

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
201625772010MUC12 mRNA expression is an independent marker of prognosis in stage II and stage III colorectal cancer.39
188340732008Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.10
267700202015Differential Expression of MUC12, MUC16, and MUC20 in Patients with Active and Remission Ulcerative Colitis.8
304815382019Shared expression of mucin12 in Ascaris lumbricoides and the human small intestine.0

Citation

Dessen P

MUC12 (mucin 12, cell surface associated)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70581/muc12