MYCNOS (MYCN opposite strand)

2003-06-01  

Identity

HGNC
LOCATION
2p24.3
LOCUSID
ALIAS
MYCN-AS1,N-CYM,NCYM,NYCM

Other Information

Locus ID:

NCBI: 10408
MIM: 605374
HGNC: 16911
Ensembl: ENSG00000233718

Variants:

dbSNP: 10408
ClinVar: 10408
TCGA: ENSG00000233718
COSMIC: MYCNOS

RNA/Proteins

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10

References

Pubmed IDYearTitleCitations
243915092014NCYM, a Cis-antisense gene of MYCN, encodes a de novo evolved protein that inhibits GSK3β resulting in the stabilization of MYCN in human neuroblastomas.23
258809092015Functional interplay between MYCN, NCYM, and OCT4 promotes aggressiveness of human neuroblastomas.13
277488062016NCYM is upregulated by lncUSMycN and modulates N-Myc expression.6
297722372018LSINCT5 activates Wnt/β-catenin signaling by interacting with NCYM to promote bladder cancer progression.5
294669622018The long non-coding RNA MYCNOS-01 regulates MYCN protein levels and affects growth of MYCN-amplified rhabdomyosarcoma and neuroblastoma cells.4
308646752019Targeting excessive MYCN expression using MLN8237 and JQ1 impairs the growth of hepatoblastoma cells.2
314270862019TAp63 represses transcription of MYCN/NCYM gene and its high levels of expression are associated with favorable outcome in neuroblastoma.0

Citation

Dessen P

MYCNOS (MYCN opposite strand)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41474/mycnos