Identity
HGNC
LOCATION
2q34
LOCUSID
ALIAS
MLC1F,MLC3F,MYOFTA
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4632
MIM: 160780
HGNC: 7582
Ensembl: ENSG00000168530
Variants:
dbSNP: 4632
ClinVar: 4632
TCGA: ENSG00000168530
COSMIC: MYL1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000168530 | ENST00000341685 | P05976 |
| ENSG00000168530 | ENST00000352451 | P05976 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Muscle contraction | REACTOME | R-HSA-397014 |
| Striated Muscle Contraction | REACTOME | R-HSA-390522 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37679666 | 2023 | Analysis of myosin genes in HNSCC and identify MYL1 as a specific poor prognostic biomarker, promotes tumor metastasis and correlates with tumor immune infiltration in HNSCC. | 5 |
| 37679666 | 2023 | Analysis of myosin genes in HNSCC and identify MYL1 as a specific poor prognostic biomarker, promotes tumor metastasis and correlates with tumor immune infiltration in HNSCC. | 5 |
| 33499774 | 2021 | MYBPC2 and MYL1 as Significant Gene Markers for Rhabdomyosarcoma. | 6 |
| 34596111 | 2021 | MYL2 as a potential predictive biomarker for rhabdomyosarcoma. | 1 |
| 33499774 | 2021 | MYBPC2 and MYL1 as Significant Gene Markers for Rhabdomyosarcoma. | 6 |
| 34596111 | 2021 | MYL2 as a potential predictive biomarker for rhabdomyosarcoma. | 1 |
| 29102634 | 2018 | Transient interaction between the N-terminal extension of the essential light chain-1 and motor domain of the myosin head during the ATPase cycle. | 2 |
| 30215711 | 2018 | Bi-allelic mutations in MYL1 cause a severe congenital myopathy. | 19 |
| 29102634 | 2018 | Transient interaction between the N-terminal extension of the essential light chain-1 and motor domain of the myosin head during the ATPase cycle. | 2 |
| 30215711 | 2018 | Bi-allelic mutations in MYL1 cause a severe congenital myopathy. | 19 |
| 26473445 | 2017 | Intron polymorphism in MYL1 gene is associated with individual cardiac trainability to endurance training in human myocardium. | 3 |
| 28427997 | 2017 | Distinct sequences and post-translational modifications in cardiac atrial and ventricular myosin light chains revealed by top-down mass spectrometry. | 21 |
| 28618653 | 2017 | Myosin regulatory light chain phosphorylation is associated with leiomyosarcoma development. | 5 |
| 26473445 | 2017 | Intron polymorphism in MYL1 gene is associated with individual cardiac trainability to endurance training in human myocardium. | 3 |
| 28427997 | 2017 | Distinct sequences and post-translational modifications in cardiac atrial and ventricular myosin light chains revealed by top-down mass spectrometry. | 21 |
Citation
Dessen P
MYL1 (myosin light chain 1)
Atlas Genet Cytogenet Oncol Haematol. 2008-07-01
Online version: http://atlasgeneticsoncology.org/gene/50200/myl1
