MYL6B (myosin light chain 6B)

2019-05-01  

Identity

HGNC
LOCATION
12q13.2
LOCUSID
ALIAS
MLC1SA

Other Information

Locus ID:

NCBI: 140465
MIM: 609930
HGNC: 29823
Ensembl: ENSG00000196465

Variants:

dbSNP: 140465
ClinVar: 140465
TCGA: ENSG00000196465
COSMIC: MYL6B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196465ENST00000550443P14649
ENSG00000196465ENST00000550443A0A024RB31
ENSG00000196465ENST00000551834F8VSA2
ENSG00000196465ENST00000552568F8W1I5
ENSG00000196465ENST00000553066P14649
ENSG00000196465ENST00000553066A0A024RB31

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Tight junctionKEGGko04530
Tight junctionKEGGhsa04530
Vascular smooth muscle contractionKEGGhsa04270
Vascular smooth muscle contractionKEGGko04270
Oxytocin signaling pathwayKEGGhsa04921
Oxytocin signaling pathwayKEGGko04921
Muscle contractionREACTOMER-HSA-397014
Smooth Muscle ContractionREACTOMER-HSA-445355

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
185876282008IQ motif selectivity in human IQGAP1: binding of myosin essential light chain and S100B.9
294397192018MYL6B, a myosin light chain, promotes MDM2-mediated p53 degradation and drives HCC development.3

Citation

Dessen P

MYL6B (myosin light chain 6B)

Atlas Genet Cytogenet Oncol Haematol. 2019-05-01

Online version: http://atlasgeneticsoncology.org/gene/57982/myl6b