Identity
HGNC
LOCATION
16q11.2
LOCUSID
ALIAS
MLCK,MLCK2,caMLCK
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 91807
MIM: 612147
HGNC: 29826
Ensembl: ENSG00000140795
Variants:
dbSNP: 91807
ClinVar: 91807
TCGA: ENSG00000140795
COSMIC: MYLK3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000140795 | ENST00000394809 | Q32MK0 |
| ENSG00000140795 | ENST00000536476 | Q32MK0 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 29235529 | 2017 | Identification of MYLK3 mutations in familial dilated cardiomyopathy. | 17 |
| 29235529 | 2017 | Identification of MYLK3 mutations in familial dilated cardiomyopathy. | 17 |
| 24722904 | 2014 | Cyclic stretch disrupts apical junctional complexes in Caco-2 cell monolayers by a JNK-2-, c-Src-, and MLCK-dependent mechanism. | 34 |
| 24722904 | 2014 | Cyclic stretch disrupts apical junctional complexes in Caco-2 cell monolayers by a JNK-2-, c-Src-, and MLCK-dependent mechanism. | 34 |
| 23591626 | 2013 | Hepatitis B virus X protein disrupts stress fiber formation and triggers apoptosis. | 2 |
| 23863751 | 2013 | Biochemical and physiological regulation of cardiac myocyte contraction by cardiac-specific myosin light chain kinase. | 14 |
| 23591626 | 2013 | Hepatitis B virus X protein disrupts stress fiber formation and triggers apoptosis. | 2 |
| 23863751 | 2013 | Biochemical and physiological regulation of cardiac myocyte contraction by cardiac-specific myosin light chain kinase. | 14 |
| 18390750 | 2008 | Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability. | 172 |
| 18390750 | 2008 | Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability. | 172 |
| 17885681 | 2007 | A cardiac myosin light chain kinase regulates sarcomere assembly in the vertebrate heart. | 80 |
| 17885681 | 2007 | A cardiac myosin light chain kinase regulates sarcomere assembly in the vertebrate heart. | 80 |
Citation
Dessen P
MYLK3 (myosin light chain kinase 3)
Atlas Genet Cytogenet Oncol Haematol. 2011-01-01
Online version: http://atlasgeneticsoncology.org/gene/51891/mylk3
