MYT1L (myelin transcription factor 1 like)

2013-12-01  

Identity

HGNC
MYT1L
LOCATION
2p25.3
LOCUSID
23040
ALIAS
MRD39,NZF1,ZC2H2C2,ZC2HC4B,myT1-L
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23040
MIM: 613084
HGNC: 7623
Ensembl: ENSG00000186487

Variants:

dbSNP: 23040
ClinVar: 23040
TCGA: ENSG00000186487
COSMIC: MYT1L

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000186487ENST00000399157H7BYU4
ENSG00000186487ENST00000399161Q9UL68
ENSG00000186487ENST00000407844Q9UL68
ENSG00000186487ENST00000428368Q9UL68
ENSG00000186487ENST00000470954A0A3B3ISB6
ENSG00000186487ENST00000471668Q49A74
ENSG00000186487ENST00000485348A0A3B3IRJ2
ENSG00000186487ENST00000490585A0A3B3IS21
ENSG00000186487ENST00000602387R4GMY9
ENSG00000186487ENST00000644820A0A2R8YF72
ENSG00000186487ENST00000647618A0A3B3IRT9
ENSG00000186487ENST00000647687A0A3B3IU83
ENSG00000186487ENST00000647694Q9UL68
ENSG00000186487ENST00000647738Q9UL68
ENSG00000186487ENST00000647755A0A3B3IRX5
ENSG00000186487ENST00000647848A0A3B3IRR4
ENSG00000186487ENST00000648316Q9UL68
ENSG00000186487ENST00000648318A0A3B3IRM3
ENSG00000186487ENST00000648339A0A3B3ISW5
ENSG00000186487ENST00000648366A0A3B3IRQ0
ENSG00000186487ENST00000648430A0A3B3ISP2
ENSG00000186487ENST00000648627A0A3B3ISN3
ENSG00000186487ENST00000648665A0A3B3IS61
ENSG00000186487ENST00000648753A0A3B3IS77
ENSG00000186487ENST00000648885A0A3B3ISG9
ENSG00000186487ENST00000648928Q9UL68
ENSG00000186487ENST00000648931A0A3B3IUE2
ENSG00000186487ENST00000648933A0A3B3ITL3
ENSG00000186487ENST00000648943A0A3B3IRX0
ENSG00000186487ENST00000649092A0A3B3ISI4
ENSG00000186487ENST00000649207Q9UL68
ENSG00000186487ENST00000649313A0A3B3IRK4
ENSG00000186487ENST00000649587A0A3B3ISU9
ENSG00000186487ENST00000649641A0A3B3ISN1
ENSG00000186487ENST00000649663A0A3B3ISW5
ENSG00000186487ENST00000649709A0A3B3ISU4
ENSG00000186487ENST00000649741A0A3B3IS97
ENSG00000186487ENST00000649810A0A3B3IU66
ENSG00000186487ENST00000649840A0A3B3IRF0
ENSG00000186487ENST00000650081A0A3B3ITT2
ENSG00000186487ENST00000650399A0A3B3ITS6
ENSG00000186487ENST00000650485A0A3B3IS14
ENSG00000186487ENST00000650560A0A3B3ITJ8
ENSG00000186487ENST00000650589A0A3B3IT20

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA448320allopurinolChemicalClinicalAnnotationassociatedPD30924126

References

Pubmed IDYearTitleCitations
189403112008Recurrent CNVs disrupt three candidate genes in schizophrenia patients.107
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
271533972016Mechanisms and Disease Associations of Haplotype-Dependent Allele-Specific DNA Methylation.35
239183702013From the Cover: Neutralization of terminal differentiation in gliomagenesis.34
219901402011MYT1L is a candidate gene for intellectual disability in patients with 2p25.3 (2pter) deletions.23
225471392012Microduplications disrupting the MYT1L gene (2p25.3) are associated with schizophrenia.20
252328462015Refinement of the critical 2p25.3 deletion region: the role of MYT1L in intellectual disability and obesity.14
210489712010Common SNPs in myelin transcription factor 1-like (MYT1L): association with major depressive disorder in the Chinese Han population.10
210489712010Common SNPs in myelin transcription factor 1-like (MYT1L): association with major depressive disorder in the Chinese Han population.10
219237612012Association study of myelin transcription factor 1-like polymorphisms with schizophrenia in Han Chinese population.10

Citation

Dessen P

MYT1L (myelin transcription factor 1 like)

Atlas Genet Cytogenet Oncol Haematol. 2013-12-01

Online version: http://atlasgeneticsoncology.org/gene/53639/myt1l