NAA25 (N-alpha-acetyltransferase 25, NatB auxiliary subunit)

2014-11-01  

Identity

HGNC
NAA25
LOCATION
12q24.13
LOCUSID
80018
ALIAS
C12orf30,MDM20,NAP1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 80018
MIM: 612755
HGNC: 25783
Ensembl: ENSG00000111300

Variants:

dbSNP: 80018
ClinVar: 80018
TCGA: ENSG00000111300
COSMIC: NAA25

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000111300ENST00000261745Q14CX7
ENSG00000111300ENST00000547133H0YHR9
ENSG00000111300ENST00000549711F8VSB9
ENSG00000111300ENST00000551858F8W0N5

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
228143782012N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.56
185706292008Identification of the human N(alpha)-acetyltransferase complex B (hNatB): a complex important for cell-cycle progression.46
185706292008Identification of the human N(alpha)-acetyltransferase complex B (hNatB): a complex important for cell-cycle progression.46
205495152010Genome-wide searching of rare genetic variants in WTCCC data.29
195655002009Variants in TNFAIP3, STAT4, and C12orf30 loci associated with multiple autoimmune diseases are also associated with juvenile idiopathic arthritis.28
195655002009Variants in TNFAIP3, STAT4, and C12orf30 loci associated with multiple autoimmune diseases are also associated with juvenile idiopathic arthritis.28
209628502011A targeted association study in systemic lupus erythematosus identifies multiple susceptibility alleles.21
202035242010Genetic susceptibility to type 2 diabetes is associated with reduced prostate cancer risk.16
200891782010Allelic variants in the PHTF1-PTPN22, C12orf30 and CD226 regions as candidate susceptibility factors for the type 1 diabetes in the Estonian population.5
266003892015Mdm20 Modulates Actin Remodeling through the mTORC2 Pathway via Its Effect on Rictor Expression.1

Citation

Dessen P

NAA25 (N-alpha-acetyltransferase 25, NatB auxiliary subunit)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70657/naa25