NAAA (N-acylethanolamine acid amidase)

2009-03-01  

Identity

HGNC
LOCATION
4q21.1
LOCUSID
ALIAS
ASAHL,PLT
FUSION GENES

Other Information

Locus ID:

NCBI: 27163
MIM: 607469
HGNC: 736
Ensembl: ENSG00000138744

Variants:

dbSNP: 27163
ClinVar: 27163
TCGA: ENSG00000138744
COSMIC: NAAA

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000138744ENST00000286733Q02083
ENSG00000138744ENST00000505594B4DVL2
ENSG00000138744ENST00000507187D6R9S9
ENSG00000138744ENST00000507956Q02083
ENSG00000138744ENST00000513045H0Y988
ENSG00000138744ENST00000602782R4GNC0

Expression (GTEx)

0
5
10
15
20
25
30
35

Pathways

PathwaySourceExternal ID
Neuronal SystemREACTOMER-HSA-112316
Transmission across Chemical SynapsesREACTOMER-HSA-112315
Neurotransmitter Release CycleREACTOMER-HSA-112310

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
247411142014Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness.67
156101812004Elevation of the level and activity of acid ceramidase in Alzheimer's disease brain.15
188062702008Expression and secretion of N-acylethanolamine-hydrolysing acid amidase in human prostate cancer cells.14
179801702007Proteolytic activation and glycosylation of N-acylethanolamine-hydrolyzing acid amidase, a lysosomal enzyme involved in the endocannabinoid metabolism.12
190146332008Lack of association of genetic variants in genes of the endocannabinoid system with anorexia nervosa.11
220401712012Mass spectrometric characterization of human N-acylethanolamine-hydrolyzing acid amidase.9
180209492007Overexpression and mass spectrometry analysis of mature human acid ceramidase.8
276932422016A quantitative study on splice variants of N-acylethanolamine acid amidase in human prostate cancer cells and other cells.1
317507362019Genetic Polymorphisms on 4q21.1 Contributed to the Risk of Hashimoto's Thyroiditis.0

Citation

Dessen P

NAAA (N-acylethanolamine acid amidase)

Atlas Genet Cytogenet Oncol Haematol. 2009-03-01

Online version: http://atlasgeneticsoncology.org/gene/50702/naaa