NAF1 (nuclear assembly factor 1 ribonucleoprotein)

2014-06-01  

Identity

HGNC
LOCATION
4q32.2
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 92345
MIM: 617868
HGNC: 25126
Ensembl: ENSG00000145414

Variants:

dbSNP: 92345
ClinVar: 92345
TCGA: ENSG00000145414
COSMIC: NAF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000145414ENST00000274054Q96HR8
ENSG00000145414ENST00000422287Q96HR8
ENSG00000145414ENST00000509434D6RIB3

Expression (GTEx)

0
5
10
15
20

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
275109032016Loss-of-function mutations in the RNA biogenesis factor NAF1 predispose to pulmonary fibrosis-emphysema.53
276214392016Breast cancer tumorigenicity is dependent on high expression levels of NAF-1 and the lability of its Fe-S clusters.16
303250192019Genetic determinants of telomere length and risk of pancreatic cancer: A PANDoRA study.6
265814172015U-shaped association between telomere length and esophageal squamous cell carcinoma risk: a case-control study in Chinese population.3
207973172010Analysis of copy number variation in 8,842 Korean individuals reveals 39 genes associated with hepatic biomarkers AST and ALT.2
284540862017Association between genetic variants and esophageal cancer risk.1

Citation

Dessen P

NAF1 (nuclear assembly factor 1 ribonucleoprotein)

Atlas Genet Cytogenet Oncol Haematol. 2014-06-01

Online version: http://atlasgeneticsoncology.org/gene/54034/naf1