Identity
HGNC
LOCATION
5q13.2
LOCUSID
ALIAS
BIRC1,NLRB1,psiNAIP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4671
MIM: 600355
HGNC: 7634
Ensembl: ENSG00000249437
Variants:
dbSNP: 4671
ClinVar: 4671
TCGA: ENSG00000249437
COSMIC: NAIP
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| NOD-like receptor signaling pathway | KEGG | ko04621 |
| NOD-like receptor signaling pathway | KEGG | hsa04621 |
| Legionellosis | KEGG | ko05134 |
| Legionellosis | KEGG | hsa05134 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37267294 | 2023 | Pan-cancer analysis of the intervertebral-disc-degeneration-related innate immunity gene NAIP. | 0 |
| 37586642 | 2023 | Targeting Desulfovibrio vulgaris flagellin-induced NAIP/NLRC4 inflammasome activation in macrophages attenuates ulcerative colitis. | 1 |
| 37750622 | 2023 | Deletions of SMNI gene exon 7 and NAIP gene exon 5 in spinal muscular atrophy patients in selected population. | 1 |
| 37267294 | 2023 | Pan-cancer analysis of the intervertebral-disc-degeneration-related innate immunity gene NAIP. | 0 |
| 37586642 | 2023 | Targeting Desulfovibrio vulgaris flagellin-induced NAIP/NLRC4 inflammasome activation in macrophages attenuates ulcerative colitis. | 1 |
| 37750622 | 2023 | Deletions of SMNI gene exon 7 and NAIP gene exon 5 in spinal muscular atrophy patients in selected population. | 1 |
| 35678562 | 2022 | Salmonella enterica Serovar Typhimurium Induces NAIP/NLRC4- and NLRP3/ASC-Independent, Caspase-4-Dependent Inflammasome Activation in Human Intestinal Epithelial Cells. | 19 |
| 35678562 | 2022 | Salmonella enterica Serovar Typhimurium Induces NAIP/NLRC4- and NLRP3/ASC-Independent, Caspase-4-Dependent Inflammasome Activation in Human Intestinal Epithelial Cells. | 19 |
| 33846244 | 2021 | Bacterial detection by NAIP/NLRC4 elicits prompt contractions of intestinal epithelial cell layers. | 22 |
| 33846244 | 2021 | Bacterial detection by NAIP/NLRC4 elicits prompt contractions of intestinal epithelial cell layers. | 22 |
| 32011487 | 2020 | The analysis of the association between the copy numbers of survival motor neuron gene 2 and neuronal apoptosis inhibitory protein genes and the clinical phenotypes in 40 patients with spinal muscular atrophy: Observational study. | 8 |
| 32011487 | 2020 | The analysis of the association between the copy numbers of survival motor neuron gene 2 and neuronal apoptosis inhibitory protein genes and the clinical phenotypes in 40 patients with spinal muscular atrophy: Observational study. | 8 |
| 29311650 | 2018 | Neuronal apoptosis inhibitory protein is implicated in amyotrophic lateral sclerosis symptoms. | 6 |
| 29518103 | 2018 | Inhibitor of apoptosis proteins, NAIP, cIAP1 and cIAP2 expression during macrophage differentiation and M1/M2 polarization. | 16 |
| 29311650 | 2018 | Neuronal apoptosis inhibitory protein is implicated in amyotrophic lateral sclerosis symptoms. | 6 |
Citation
Dessen P
NAIP (NLR family apoptosis inhibitory protein)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43168/naip
