NAP1L1 (nucleosome assembly protein 1 like 1)

2012-07-01 Affiliation

Identity

HGNC

NAP1L1

LOCATION

12q21.2

LOCUSID

4673

ALIAS

NAP1,NAP1L,NRP

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 4673
MIM: 164060
HGNC: 7637
Ensembl: ENSG00000187109

Variants:

dbSNP: 4673
ClinVar: 4673
TCGA: ENSG00000187109
COSMIC: NAP1L1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000187109	ENST00000261182	P55209
ENSG00000187109	ENST00000261182	A0A024RBB7
ENSG00000187109	ENST00000393263	P55209
ENSG00000187109	ENST00000393263	A0A024RBB7
ENSG00000187109	ENST00000431879	P55209
ENSG00000187109	ENST00000535020	F5H4R6
ENSG00000187109	ENST00000542344	B7Z9C2
ENSG00000187109	ENST00000544816	B7Z4K9
ENSG00000187109	ENST00000547479	F8VVB5
ENSG00000187109	ENST00000547529	H0YH88
ENSG00000187109	ENST00000547704	F8W020
ENSG00000187109	ENST00000547773	F8W543
ENSG00000187109	ENST00000548044	F8VV59
ENSG00000187109	ENST00000548273	F8W118
ENSG00000187109	ENST00000549596	P55209
ENSG00000187109	ENST00000550934	F8VUX1
ENSG00000187109	ENST00000551524	F8VRJ2
ENSG00000187109	ENST00000551600	F8VXI6
ENSG00000187109	ENST00000551992	F8VY35
ENSG00000187109	ENST00000552056	H0YIV4
ENSG00000187109	ENST00000552147	H0YHC3
ENSG00000187109	ENST00000552342	F8W0J6
ENSG00000187109	ENST00000618691	P55209
ENSG00000187109	ENST00000618691	A0A024RBB7

Expression (GTEx)

100

150

200

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
14966293	2004	Direct interaction between nucleosome assembly protein 1 and the papillomavirus E2 proteins involved in activation of transcription.	34
16287874	2005	Assembly and disassembly of nucleosome core particles containing histone variants by human nucleosome assembly protein I.	32
30165194	2018	LncRNA CDKN2B-AS1 promotes tumor growth and metastasis of human hepatocellular carcinoma by targeting let-7c-5p/NAP1L1 axis.	23
20002496	2010	Functional characterization of human nucleosome assembly protein 1-like proteins as histone chaperones.	21
17339334	2007	The nucleosome assembly activity of NAP1 is enhanced by Alien.	13
21333655	2011	Interaction between nucleosome assembly protein 1-like family members.	11
24798879	2014	Nap1 stimulates homologous recombination by RAD51 and RAD54 in higher-ordered chromatin containing histone H1.	9
28659470	2017	Hepatitis C Virus NS5A Targets Nucleosome Assembly Protein NAP1L1 To Control the Innate Cellular Response.	7
28369616	2017	NAP1L1 accelerates activation and decreases pausing to enhance nucleosome remodeling by CSB.	6
29572888	2018	PRDM8 exhibits antitumor activities toward hepatocellular carcinoma by targeting NAP1L1.	6

Citation

Dessen P

NAP1L1 (nucleosome assembly protein 1 like 1)

Atlas Genet Cytogenet Oncol Haematol. 2012-07-01

Online version: http://atlasgeneticsoncology.org/gene/52770/nap1l1