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NAP1L4 (nucleosome assembly protein 1 like 4)

Identity

Alias_namesnucleosome assembly protein 1-like 4
Alias_symbol (synonym)NAP2
Other aliasNAP1L4b
NAP2L
hNAP2
HGNC (Hugo) NAP1L4
LocusID (NCBI) 4676
Atlas_Id 41494
Location 11p15.4  [Link to chromosome band 11p15]
Location_base_pair Starts at 2944430 and ends at 2992377 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CRIP2 (14q32.33) / NAP1L4 (11p15.4)NAP1L4 (11p15.4) / CARS (11p15.4)NAP1L4 (11p15.4) / CNBP (3q21.3)
NAP1L4 (11p15.4) / MBP (18q23)NAP1L4 (11p15.4) / NAP1L4 (11p15.4)NAP1L4 (11p15.4) / RPAP1 (15q15.1)
NAP1L4 (11p15.4) / TTC12 (11q23.2)NAP1L4 (11p15.4) / UBE2R2 (9p13.3)SOD1 (21q22.11) / NAP1L4 (11p15.4)
NAP1L4 11p15.4 / CARS 11p15.4NAP1L4 11p15.4 / RPAP1 15q15.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  NAP1L4/CARS (11p15)
t(11;15)(p15;q15) NAP1L4/RPAP1

External links

Nomenclature
HGNC (Hugo)NAP1L4   7640
Cards
Entrez_Gene (NCBI)NAP1L4  4676  nucleosome assembly protein 1 like 4
AliasesNAP1L4b; NAP2; NAP2L; hNAP2
GeneCards (Weizmann)NAP1L4
Ensembl hg19 (Hinxton)ENSG00000205531 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000205531 [Gene_View]  ENSG00000205531 [Sequence]  chr11:2944430-2992377 [Contig_View]  NAP1L4 [Vega]
ICGC DataPortalENSG00000205531
TCGA cBioPortalNAP1L4
AceView (NCBI)NAP1L4
Genatlas (Paris)NAP1L4
WikiGenes4676
SOURCE (Princeton)NAP1L4
Genetics Home Reference (NIH)NAP1L4
Genomic and cartography
GoldenPath hg38 (UCSC)NAP1L4  -     chr11:2944430-2992377 -  11p15.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NAP1L4  -     11p15.4   [Description]    (hg19-Feb_2009)
GoldenPathNAP1L4 - 11p15.4 [CytoView hg19]  NAP1L4 - 11p15.4 [CytoView hg38]
ImmunoBaseENSG00000205531
Mapping of homologs : NCBINAP1L4 [Mapview hg19]  NAP1L4 [Mapview hg38]
OMIM601651   
Gene and transcription
Genbank (Entrez)AA573896 AB362575 AB500094 AK056828 AK093928
RefSeq transcript (Entrez)NM_001369375 NM_001369376 NM_001369377 NM_001369378 NM_001369379 NM_001369380 NM_001369381 NM_001369382 NM_001369383 NM_001369384 NM_001369385 NM_001369386 NM_001369388 NM_005969
RefSeq genomic (Entrez)NC_000011 NT_187585
Consensus coding sequences : CCDS (NCBI)NAP1L4
Cluster EST : UnigeneHs.731784 [ NCBI ]
CGAP (NCI)Hs.731784
Alternative Splicing GalleryENSG00000205531
Gene ExpressionNAP1L4 [ NCBI-GEO ]   NAP1L4 [ EBI - ARRAY_EXPRESS ]   NAP1L4 [ SEEK ]   NAP1L4 [ MEM ]
Gene Expression Viewer (FireBrowse)NAP1L4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4676
GTEX Portal (Tissue expression)NAP1L4
Human Protein AtlasENSG00000205531-NAP1L4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99733   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99733  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99733
Splice isoforms : SwissVarQ99733
PhosPhoSitePlusQ99733
Domains : Interpro (EBI)NAP-like_sf    NAP_family   
Domain families : Pfam (Sanger)NAP (PF00956)   
Domain families : Pfam (NCBI)pfam00956   
Conserved Domain (NCBI)NAP1L4
DMDM Disease mutations4676
Blocks (Seattle)NAP1L4
SuperfamilyQ99733
Human Protein Atlas [tissue]ENSG00000205531-NAP1L4 [tissue]
Peptide AtlasQ99733
HPRD11873
IPIIPI00941463   IPI00017763   IPI00848341   IPI00798071   IPI00788840   IPI00789437   IPI00980509   IPI01014729   IPI00979151   IPI00979847   IPI00790016   IPI00983980   IPI01009760   IPI01010987   IPI00984634   IPI00978457   
Protein Interaction databases
DIP (DOE-UCLA)Q99733
IntAct (EBI)Q99733
FunCoupENSG00000205531
BioGRIDNAP1L4
STRING (EMBL)NAP1L4
ZODIACNAP1L4
Ontologies - Pathways
QuickGOQ99733
Ontology : AmiGORNA binding  protein binding  nucleus  cytoplasm  nucleosome assembly  nucleosome binding  unfolded protein binding  
Ontology : EGO-EBIRNA binding  protein binding  nucleus  cytoplasm  nucleosome assembly  nucleosome binding  unfolded protein binding  
NDEx NetworkNAP1L4
Atlas of Cancer Signalling NetworkNAP1L4
Wikipedia pathwaysNAP1L4
Orthology - Evolution
OrthoDB4676
GeneTree (enSembl)ENSG00000205531
Phylogenetic Trees/Animal Genes : TreeFamNAP1L4
HOGENOMQ99733
Homologs : HomoloGeneNAP1L4
Homology/Alignments : Family Browser (UCSC)NAP1L4
Gene fusions - Rearrangements
Fusion : MitelmanNAP1L4/CARS [11p15.4/11p15.4]  
Fusion : MitelmanNAP1L4/RPAP1 [11p15.4/15q15.1]  [t(11;15)(p15;q15)]  
Fusion PortalNAP1L4 11p15.4 CARS 11p15.4 BRCA
Fusion PortalNAP1L4 11p15.4 RPAP1 15q15.1 BRCA
Fusion : QuiverNAP1L4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNAP1L4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NAP1L4
dbVarNAP1L4
ClinVarNAP1L4
1000_GenomesNAP1L4 
Exome Variant ServerNAP1L4
ExAC (Exome Aggregation Consortium)ENSG00000205531
GNOMAD BrowserENSG00000205531
Varsome BrowserNAP1L4
Genetic variants : HAPMAP4676
Genomic Variants (DGV)NAP1L4 [DGVbeta]
DECIPHERNAP1L4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNAP1L4 
Mutations
ICGC Data PortalNAP1L4 
TCGA Data PortalNAP1L4 
Broad Tumor PortalNAP1L4
OASIS PortalNAP1L4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNAP1L4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNAP1L4
Mutations and Diseases : HGMDNAP1L4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NAP1L4
DgiDB (Drug Gene Interaction Database)NAP1L4
DoCM (Curated mutations)NAP1L4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NAP1L4 (select a term)
intoGenNAP1L4
Cancer3DNAP1L4(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601651   
Orphanet
DisGeNETNAP1L4
MedgenNAP1L4
Genetic Testing Registry NAP1L4
NextProtQ99733 [Medical]
TSGene4676
GENETestsNAP1L4
Target ValidationNAP1L4
Huge Navigator NAP1L4 [HugePedia]
snp3D : Map Gene to Disease4676
BioCentury BCIQNAP1L4
ClinGenNAP1L4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4676
Chemical/Pharm GKB GenePA31442
Clinical trialNAP1L4
Miscellaneous
canSAR (ICR)NAP1L4 (select the gene name)
DataMed IndexNAP1L4
Probes
Litterature
PubMed63 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNAP1L4
EVEXNAP1L4
GoPubMedNAP1L4
iHOPNAP1L4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:57:12 CET 2019
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