NAP1L4 (nucleosome assembly protein 1 like 4)

2003-06-01  

Identity

HGNC
NAP1L4
LOCATION
11p15.4
LOCUSID
4676
ALIAS
NAP1L4b,NAP2,NAP2L,hNAP2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4676
MIM: 601651
HGNC: 7640
Ensembl: ENSG00000205531

Variants:

dbSNP: 4676
ClinVar: 4676
TCGA: ENSG00000205531
COSMIC: NAP1L4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000205531ENST00000380542Q99733
ENSG00000205531ENST00000380542A0A024RCC9
ENSG00000205531ENST00000399614A8MXH2
ENSG00000205531ENST00000430811C9J6D1
ENSG00000205531ENST00000448187C9JZI7
ENSG00000205531ENST00000455338C9J1B1
ENSG00000205531ENST00000492685H0YCI4
ENSG00000205531ENST00000526115Q99733
ENSG00000205531ENST00000526842E9PJJ2
ENSG00000205531ENST00000528968E9PNJ7
ENSG00000205531ENST00000529361E9PKT8
ENSG00000205531ENST00000530064E9PS34
ENSG00000205531ENST00000531291E9PNW0
ENSG00000205531ENST00000532325E9PP22
ENSG00000205531ENST00000534372E9PKI2
ENSG00000205531ENST00000620138Q99733

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
202019242010Genome-wide association study of alcohol dependence implicates a region on chromosome 11.159
182816992008Nucleosome formation with the testis-specific histone H3 variant, H3t, by human nucleosome assembly proteins in vitro.22
200024962010Functional characterization of human nucleosome assembly protein 1-like proteins as histone chaperones.21
213336552011Interaction between nucleosome assembly protein 1-like family members.11
206447302010Telomeric NAP1L4 and OSBPL5 of the KCNQ1 cluster, and the DECORIN gene are not imprinted in human trophoblast stem cells.4
153683652004NAP-2 is part of multi-protein complexes in HeLa cells.3
286872762017NAP1L1 regulates NF-κB signaling pathway acting on anti-apoptotic Mcl-1 gene expression.1
316345042019Nucleosome assembly proteins NAP1L1 and NAP1L4 modulate p53 acetylation to regulate cell fate.0

Citation

Dessen P

NAP1L4 (nucleosome assembly protein 1 like 4)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41494/nap1l4