NASP (nuclear autoantigenic sperm protein)

2003-06-01  

Identity

HGNC
LOCATION
1p34.1
LOCUSID
ALIAS
FLB7527,HMDRA1,PRO1999
FUSION GENES

Other Information

Locus ID:

NCBI: 4678
MIM: 603185
HGNC: 7644
Ensembl: ENSG00000132780

Variants:

dbSNP: 4678
ClinVar: 4678
TCGA: ENSG00000132780
COSMIC: NASP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132780ENST00000350030P49321
ENSG00000132780ENST00000351223P49321
ENSG00000132780ENST00000351223Q5T626
ENSG00000132780ENST00000372052Q5T624
ENSG00000132780ENST00000437362E9PAU3
ENSG00000132780ENST00000437901E9PI86
ENSG00000132780ENST00000453748E9PAU3
ENSG00000132780ENST00000470768E9PPR5
ENSG00000132780ENST00000525515E9PPQ8
ENSG00000132780ENST00000527359E9PQG5
ENSG00000132780ENST00000527470E9PNB5
ENSG00000132780ENST00000528084E9PKR5
ENSG00000132780ENST00000528238E9PRH9
ENSG00000132780ENST00000529333E9PAU3
ENSG00000132780ENST00000530840E9PJQ2
ENSG00000132780ENST00000531532E9PKR5
ENSG00000132780ENST00000531612H0YF33
ENSG00000132780ENST00000534450H0YDS9
ENSG00000132780ENST00000537798P49321
ENSG00000132780ENST00000629893E9PKR5

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
167283912006Nuclear autoantigenic sperm protein (NASP), a linker histone chaperone that is required for cell proliferation.45
221959652011A specific function for the histone chaperone NASP to fine-tune a reservoir of soluble H3-H4 in the histone supply chain.45
187828342008Expanded binding specificity of the human histone chaperone NASP.25
201675972010Nucleosome formation activity of human somatic nuclear autoantigenic sperm protein (sNASP).20
229689122012Vertebrate nucleoplasmin and NASP: egg histone storage proteins with multiple chaperone activities.19
219655322012The human histone chaperone sNASP interacts with linker and core histones through distinct mechanisms.14
221946052012MicroRNA-29a inhibited epididymal epithelial cell proliferation by targeting nuclear autoantigenic sperm protein (NASP).14
194391022009Analysis of gene expression profiles in HeLa cells in response to overexpression or siRNA-mediated depletion of NASP.11
214962992011Depletion of the histone chaperone tNASP inhibits proliferation and induces apoptosis in prostate cancer PC-3 cells.9
249510902014Molecular evolution of NASP and conserved histone H3/H4 transport pathway.8

Citation

Dessen P

NASP (nuclear autoantigenic sperm protein)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41496/nasp