Identity
HGNC
LOCATION
17q21.31
LOCUSID
ALIAS
1A1-3B,IAI3B,M17S2,MIG19
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4077
MIM: 166945
HGNC: 6746
Ensembl: ENSG00000188554
Variants:
dbSNP: 4077
ClinVar: 4077
TCGA: ENSG00000188554
COSMIC: NBR1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Mitophagy - animal | KEGG | ko04137 |
| Mitophagy - animal | KEGG | hsa04137 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38678786 | 2024 | NBR1-mediated autophagic degradation of caspase 8 protects vascular endothelial cells against arsenite-induced apoptotic cell death. | 0 |
| 38678786 | 2024 | NBR1-mediated autophagic degradation of caspase 8 protects vascular endothelial cells against arsenite-induced apoptotic cell death. | 0 |
| 35914352 | 2022 | NBR1 mediates autophagic degradation of IRF3 to negatively regulate type I interferon production. | 4 |
| 35914352 | 2022 | NBR1 mediates autophagic degradation of IRF3 to negatively regulate type I interferon production. | 4 |
| 34471133 | 2021 | Reconstitution defines the roles of p62, NBR1 and TAX1BP1 in ubiquitin condensate formation and autophagy initiation. | 57 |
| 34488032 | 2021 | Germline mutation in the NBR1 gene involved in autophagy detected in a family with renal tumors. | 3 |
| 34471133 | 2021 | Reconstitution defines the roles of p62, NBR1 and TAX1BP1 in ubiquitin condensate formation and autophagy initiation. | 57 |
| 34488032 | 2021 | Germline mutation in the NBR1 gene involved in autophagy detected in a family with renal tumors. | 3 |
| 32577726 | 2020 | The influence of rs139416141 in neighbor of Brca1 gene (NBR1) on bone mineral density in postmenopausal Chinese women. | 0 |
| 32744342 | 2020 | Identification of putative phenotype-modifying genetic factors associated with phenotypic diversity in Brooke-Spiegler syndrome. | 2 |
| 32815800 | 2020 | An increase in p62/NBR1 levels in melioidosis patients of Sri Lanka exhibit a characteristic of potential host biomarker. | 0 |
| 32577726 | 2020 | The influence of rs139416141 in neighbor of Brca1 gene (NBR1) on bone mineral density in postmenopausal Chinese women. | 0 |
| 32744342 | 2020 | Identification of putative phenotype-modifying genetic factors associated with phenotypic diversity in Brooke-Spiegler syndrome. | 2 |
| 32815800 | 2020 | An increase in p62/NBR1 levels in melioidosis patients of Sri Lanka exhibit a characteristic of potential host biomarker. | 0 |
| 31297862 | 2019 | Depletion of NBR1 in urothelial carcinoma cells enhances rapamycin-induced apoptosis through impaired autophagy and mitochondrial dysfunction. | 6 |
Citation
Dessen P
NBR1 (NBR1 autophagy cargo receptor)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41224/nbr1
