NCALD (neurocalcin delta)

2014-11-01  

Identity

HGNC
NCALD
LOCATION
8q22.3
LOCUSID
83988
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 83988
MIM: 606722
HGNC: 7655
Ensembl: ENSG00000104490

Variants:

dbSNP: 83988
ClinVar: 83988
TCGA: ENSG00000104490
COSMIC: NCALD

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000104490ENST00000220931P61601
ENSG00000104490ENST00000220931B2RB70
ENSG00000104490ENST00000311028P61601
ENSG00000104490ENST00000311028B2RB70
ENSG00000104490ENST00000395923P61601
ENSG00000104490ENST00000395923B2RB70
ENSG00000104490ENST00000517531E5RI95
ENSG00000104490ENST00000517822A0A1B0GXG3
ENSG00000104490ENST00000518166E5RI78
ENSG00000104490ENST00000518661E5RK89
ENSG00000104490ENST00000518727E5RIG4
ENSG00000104490ENST00000519098E5RJJ6
ENSG00000104490ENST00000519508P61601
ENSG00000104490ENST00000519508B2RB70
ENSG00000104490ENST00000520346E5RFL9
ENSG00000104490ENST00000520425E5RHC8
ENSG00000104490ENST00000520690E5RIZ1
ENSG00000104490ENST00000521599P61601
ENSG00000104490ENST00000521599B2RB70
ENSG00000104490ENST00000521964E5RGZ0
ENSG00000104490ENST00000522078E5RJA1
ENSG00000104490ENST00000522206E5RIX3
ENSG00000104490ENST00000522252E5RHE8
ENSG00000104490ENST00000522448E5RIA5
ENSG00000104490ENST00000522951E5RGA9
ENSG00000104490ENST00000523923E5RJT1
ENSG00000104490ENST00000524137E5RJF1
ENSG00000104490ENST00000524209E5RI95

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Olfactory transductionKEGGko04740
Olfactory transductionKEGGhsa04740
Neuronal SystemREACTOMER-HSA-112316
Transmission across Chemical SynapsesREACTOMER-HSA-112315
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic CellREACTOMER-HSA-112314
Activation of Kainate Receptors upon glutamate bindingREACTOMER-HSA-451326
Ionotropic activity of Kainate ReceptorsREACTOMER-HSA-451306
Activation of Ca-permeable Kainate ReceptorREACTOMER-HSA-451308

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
281326872017Neurocalcin Delta Suppression Protects against Spinal Muscular Atrophy in Humans and across Species by Restoring Impaired Endocytosis.40
78524011995Calcium and membrane binding properties of bovine neurocalcin delta expressed in Escherichia coli.35
176717972007Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy.23
176717972007Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy.23
185008172008Neurocalcin delta modulation of ROS-GC1, a new model of Ca(2+) signaling.23
300765412018Investigating the possible causal association of coffee consumption with osteoarthritis risk using a Mendelian randomization analysis.3
311093312019High NCALD expression predicts poor prognosis of cytogenetic normal acute myeloid leukemia.2
231563972012[Genetic study for diabetic microvascular complications--recent advances and future perspectives].0

Citation

Dessen P

NCALD (neurocalcin delta)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70725/ncald