NCAPG2 (non-SMC condensin II complex subunit G2)

2008-12-01  

Identity

HGNC
LOCATION
7q36.3
LOCUSID
ALIAS
3KS,CAP-G2,CAPG2,LUZP5,MTB,hCAP-G2
FUSION GENES

Other Information

Locus ID:

NCBI: 54892
MIM: 608532
HGNC: 21904
Ensembl: ENSG00000146918

Variants:

dbSNP: 54892
ClinVar: 54892
TCGA: ENSG00000146918
COSMIC: NCAPG2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000146918ENST00000356309Q86XI2
ENSG00000146918ENST00000409339Q86XI2
ENSG00000146918ENST00000409423Q86XI2
ENSG00000146918ENST00000432615F8WE06
ENSG00000146918ENST00000441982H0Y6U5

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
M PhaseREACTOMER-HSA-68886
Mitotic ProphaseREACTOMER-HSA-68875
Condensation of Prophase ChromosomesREACTOMER-HSA-2299718

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
381669472024NCAPG2 promotes prostate cancer malignancy and stemness via STAT3/c-MYC signaling.0
387012612024MYC and NCAPG2 as molecular targets of colorectal cancer and gastric cancer in nursing.0
381669472024NCAPG2 promotes prostate cancer malignancy and stemness via STAT3/c-MYC signaling.0
387012612024MYC and NCAPG2 as molecular targets of colorectal cancer and gastric cancer in nursing.0
372484712023Circular RNA circ0001955 promotes cervical cancer tumorigenesis and metastasis via the miR-188-3p/NCAPG2 axis.3
375446342023The mRNA stability of NCAPG2, a novel contributor to breast invasive carcinoma, is enhanced by the RNA-binding protein PCBP2.2
372484712023Circular RNA circ0001955 promotes cervical cancer tumorigenesis and metastasis via the miR-188-3p/NCAPG2 axis.3
375446342023The mRNA stability of NCAPG2, a novel contributor to breast invasive carcinoma, is enhanced by the RNA-binding protein PCBP2.2
348180252022microRNA-375 inhibits the malignant behaviors of hepatic carcinoma cells by targeting NCAPG2.4
362651822022NCAPG2 contributes to the progression of malignant melanoma through regulating proliferation and metastasis.5
348180252022microRNA-375 inhibits the malignant behaviors of hepatic carcinoma cells by targeting NCAPG2.4
362651822022NCAPG2 contributes to the progression of malignant melanoma through regulating proliferation and metastasis.5
328974182021NCAPG2 facilitates glioblastoma cells' malignancy and xenograft tumor growth via HBO1 activation by phosphorylation.18
328974182021NCAPG2 facilitates glioblastoma cells' malignancy and xenograft tumor growth via HBO1 activation by phosphorylation.18
306094102019Mutations in NCAPG2 Cause a Severe Neurodevelopmental Syndrome that Expands the Phenotypic Spectrum of Condensinopathies.18

Citation

Dessen P

NCAPG2 (non-SMC condensin II complex subunit G2)

Atlas Genet Cytogenet Oncol Haematol. 2008-12-01

Online version: http://atlasgeneticsoncology.org/gene/50578/ncapg2