NCAPH (non-SMC condensin I complex subunit H)

2007-02-01  

Identity

HGNC
NCAPH
LOCATION
2q11.2
LOCUSID
23397
ALIAS
BRRN1,CAP-H,CAPH,MCPH23
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23397
MIM: 602332
HGNC: 1112
Ensembl: ENSG00000121152

Variants:

dbSNP: 23397
ClinVar: 23397
TCGA: ENSG00000121152
COSMIC: NCAPH

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000121152ENST00000240423Q15003
ENSG00000121152ENST00000427946Q15003
ENSG00000121152ENST00000435349H7C415
ENSG00000121152ENST00000435975C9J470
ENSG00000121152ENST00000455200E9PHA2
ENSG00000121152ENST00000456906C9JZP1

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
M PhaseREACTOMER-HSA-68886
Mitotic PrometaphaseREACTOMER-HSA-68877
Condensation of Prometaphase ChromosomesREACTOMER-HSA-2514853

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
165431522006Condensin I interacts with the PARP-1-XRCC1 complex and functions in DNA single-strand break repair.62
211510262011Caspase-3-mediated degradation of condensin Cap-H regulates mitotic cell death.16
283008282017NCAPH plays important roles in human colon cancer.14
315238452019Non-SMC condensin I complex subunit H enhances proliferation, migration, and invasion of hepatocellular carcinoma.2

Citation

Dessen P

NCAPH (non-SMC condensin I complex subunit H)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43631/ncaph