NCAPH (non-SMC condensin I complex subunit H)

2007-02-01  

Identity

HGNC
LOCATION
2q11.2
LOCUSID
ALIAS
BRRN1,CAP-H,CAPH,MCPH23
FUSION GENES

Other Information

Locus ID:

NCBI: 23397
MIM: 602332
HGNC: 1112
Ensembl: ENSG00000121152

Variants:

dbSNP: 23397
ClinVar: 23397
TCGA: ENSG00000121152
COSMIC: NCAPH

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000121152ENST00000240423Q15003
ENSG00000121152ENST00000427946Q15003
ENSG00000121152ENST00000435349H7C415
ENSG00000121152ENST00000435975C9J470
ENSG00000121152ENST00000455200E9PHA2
ENSG00000121152ENST00000456906C9JZP1

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
M PhaseREACTOMER-HSA-68886
Mitotic PrometaphaseREACTOMER-HSA-68877
Condensation of Prometaphase ChromosomesREACTOMER-HSA-2514853

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
366428442023Non-SMC condensin I complex subunit H participates in anti-programmed cell death-1 resistance of clear cell renal cell carcinomas.4
366507582023An integrative pan-cancer analysis reveals the carcinogenic effects of NCAPH in human cancer.3
366428442023Non-SMC condensin I complex subunit H participates in anti-programmed cell death-1 resistance of clear cell renal cell carcinomas.4
366507582023An integrative pan-cancer analysis reveals the carcinogenic effects of NCAPH in human cancer.3
349628232022NCAPH regulates gastric cancer progression through DNA damage response.4
349747902022NCAPH promotes cell proliferation and inhibits cell apoptosis of bladder cancer cells through MEK/ERK signaling pathway.6
356889152022NCAPH is a prognostic biomarker and associated with immune infiltrates in lung adenocarcinoma.3
363807312022NCAPH Stabilizes GEN1 in Chromatin to Resolve Ultra-Fine DNA Bridges and Maintain Chromosome Stability.4
349628232022NCAPH regulates gastric cancer progression through DNA damage response.4
349747902022NCAPH promotes cell proliferation and inhibits cell apoptosis of bladder cancer cells through MEK/ERK signaling pathway.6
356889152022NCAPH is a prognostic biomarker and associated with immune infiltrates in lung adenocarcinoma.3
363807312022NCAPH Stabilizes GEN1 in Chromatin to Resolve Ultra-Fine DNA Bridges and Maintain Chromosome Stability.4
342304502021miR-133b targets NCAPH to promote β-catenin degradation and reduce cancer stem cell maintenance in non-small cell lung cancer.14
342304502021miR-133b targets NCAPH to promote β-catenin degradation and reduce cancer stem cell maintenance in non-small cell lung cancer.14
322004712020Overexpression of MYBL2 promotes proliferation and migration of non-small-cell lung cancer via upregulating NCAPH.20

Citation

Dessen P

NCAPH (non-SMC condensin I complex subunit H)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43631/ncaph