Identity
HGNC
LOCATION
2q32.1
LOCUSID
ALIAS
HEM2,NAP1,NAP125,p125Nap1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10787
MIM: 604891
HGNC: 7666
Ensembl: ENSG00000061676
Variants:
dbSNP: 10787
ClinVar: 10787
TCGA: ENSG00000061676
COSMIC: NCKAP1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000061676 | ENST00000360982 | Q9Y2A7 |
| ENSG00000061676 | ENST00000361354 | Q9Y2A7 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37154887 | 2023 | Role of NCKAP1 in the Defective Phagocytic Function of Microglia-Like Cells Derived from Rapidly Progressing Sporadic ALS. | 2 |
| 37154887 | 2023 | Role of NCKAP1 in the Defective Phagocytic Function of Microglia-Like Cells Derived from Rapidly Progressing Sporadic ALS. | 2 |
| 34533810 | 2021 | Circ_NCKAP1 promotes skin basal cell carcinoma progression by sponging the miR-148b-5p/HSP90 axis. | 4 |
| 34533810 | 2021 | Circ_NCKAP1 promotes skin basal cell carcinoma progression by sponging the miR-148b-5p/HSP90 axis. | 4 |
| 33157009 | 2020 | NCKAP1 Disruptive Variants Lead to a Neurodevelopmental Disorder with Core Features of Autism. | 19 |
| 33157009 | 2020 | NCKAP1 Disruptive Variants Lead to a Neurodevelopmental Disorder with Core Features of Autism. | 19 |
| 30867003 | 2019 | Nck-associated protein 1 associates with HSP90 to drive metastasis in human non-small-cell lung cancer. | 32 |
| 31068575 | 2019 | NCKAP1 improves patient outcome and inhibits cell growth by enhancing Rb1/p53 activation in hepatocellular carcinoma. | 17 |
| 30867003 | 2019 | Nck-associated protein 1 associates with HSP90 to drive metastasis in human non-small-cell lung cancer. | 32 |
| 31068575 | 2019 | NCKAP1 improves patient outcome and inhibits cell growth by enhancing Rb1/p53 activation in hepatocellular carcinoma. | 17 |
| 27704267 | 2017 | MicroRNA-34c-3p promotes cell proliferation and invasion in hepatocellular carcinoma by regulation of NCKAP1 expression. | 11 |
| 27704267 | 2017 | MicroRNA-34c-3p promotes cell proliferation and invasion in hepatocellular carcinoma by regulation of NCKAP1 expression. | 11 |
| 27432794 | 2016 | The WASF3-NCKAP1-CYFIP1 Complex Is Essential for Breast Cancer Metastasis. | 45 |
| 27632392 | 2016 | The Contribution of Mosaic Variants to Autism Spectrum Disorder. | 69 |
| 27432794 | 2016 | The WASF3-NCKAP1-CYFIP1 Complex Is Essential for Breast Cancer Metastasis. | 45 |
Citation
Dessen P
NCKAP1 (NCK associated protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2012-09-01
Online version: http://atlasgeneticsoncology.org/gene/52881/nckap1
