Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

NCKAP5 (NCK associated protein 5)

Identity

Alias (NCBI)ERIH1
ERIH2
NAP5
HGNC (Hugo) NCKAP5
HGNC Alias symbNAP5
ERIH1
ERIH2
HGNC Alias nameperipheral clock protein
LocusID (NCBI) 344148
Atlas_Id 70738
Location 2q21.2  [Link to chromosome band 2q21]
Location_base_pair Starts at 132671799 and ends at 133568460 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
IMP4 (2q21.1) / NCKAP5 (2q21.2)LYPD1 (2q21.2) / NCKAP5 (2q21.2)MR1 (1q25.3) / NCKAP5 (2q21.2)
NAALADL2 (3q26.31) / NCKAP5 (2q21.2)NCKAP5 (2q21.2) / DYNC2H1 (11q22.3)NCKAP5 (2q21.2) / MALAT1 (11q13.1)
NCKAP5 (2q21.2) / MZT2A (2q21.1)NCKAP5 (2q21.2) / NCKAP5 (2q21.2)NCKAP5 (2q21.2) / SLIT3 (5q34)
OSMR (5p13.1) / NCKAP5 (2q21.2)PLXNA4 (7q32.3) / NCKAP5 (2q21.2)LYPD1 NCKAP5
OSMR NCKAP5NAALADL2 NCKAP5NCKAP5 DYNC2H1
NCKAP5 MZT2A

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 5 ]
  LYPD1/NCKAP5 (2q21)
NCKAP5/MZT2A (2q21)
t(2;3)(q21;q26) NAALADL2/NCKAP5
t(2;5)(q21;p13) OSMR/NCKAP5
t(2;11)(q21;q22) NCKAP5/DYNC2H1


External links

Nomenclature
HGNC (Hugo)NCKAP5   29847
Cards
Entrez_Gene (NCBI)NCKAP5    NCK associated protein 5
AliasesERIH1; ERIH2; NAP5
GeneCards (Weizmann)NCKAP5
Ensembl hg19 (Hinxton)ENSG00000176771 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000176771 [Gene_View]  ENSG00000176771 [Sequence]  chr2:132671799-133568460 [Contig_View]  NCKAP5 [Vega]
ICGC DataPortalENSG00000176771
TCGA cBioPortalNCKAP5
AceView (NCBI)NCKAP5
Genatlas (Paris)NCKAP5
SOURCE (Princeton)NCKAP5
Genetics Home Reference (NIH)NCKAP5
Genomic and cartography
GoldenPath hg38 (UCSC)NCKAP5  -     chr2:132671799-133568460 -  2q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NCKAP5  -     2q21.2   [Description]    (hg19-Feb_2009)
GoldenPathNCKAP5 - 2q21.2 [CytoView hg19]  NCKAP5 - 2q21.2 [CytoView hg38]
ImmunoBaseENSG00000176771
genome Data Viewer NCBINCKAP5 [Mapview hg19]  
OMIM608789   
Gene and transcription
Genbank (Entrez)AB005217 AK057980 AK092189 AK124659 AY946007
RefSeq transcript (Entrez)NM_207363 NM_207481
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NCKAP5
Alternative Splicing GalleryENSG00000176771
Gene ExpressionNCKAP5 [ NCBI-GEO ]   NCKAP5 [ EBI - ARRAY_EXPRESS ]   NCKAP5 [ SEEK ]   NCKAP5 [ MEM ]
Gene Expression Viewer (FireBrowse)NCKAP5 [ Firebrowse - Broad ]
GenevisibleExpression of NCKAP5 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)344148
GTEX Portal (Tissue expression)NCKAP5
Human Protein AtlasENSG00000176771-NCKAP5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14513   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14513  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14513
Splice isoforms : SwissVarO14513
PhosPhoSitePlusO14513
Domains : Interpro (EBI)NCKAP5_C    Nckap5l   
Domain families : Pfam (Sanger)NCKAP5 (PF15246)   
Domain families : Pfam (NCBI)pfam15246   
Conserved Domain (NCBI)NCKAP5
Blocks (Seattle)NCKAP5
SuperfamilyO14513
Human Protein Atlas [tissue]ENSG00000176771-NCKAP5 [tissue]
Peptide AtlasO14513
HPRD16936
IPIIPI00419253   IPI00807540   IPI00410416   IPI00807489   IPI01009130   
Protein Interaction databases
DIP (DOE-UCLA)O14513
IntAct (EBI)O14513
BioGRIDNCKAP5
STRING (EMBL)NCKAP5
ZODIACNCKAP5
Ontologies - Pathways
QuickGOO14513
Ontology : AmiGOmicrotubule bundle formation  cellular_component  microtubule depolymerization  biological_process  microtubule plus-end  
Ontology : EGO-EBImicrotubule bundle formation  cellular_component  microtubule depolymerization  biological_process  microtubule plus-end  
NDEx NetworkNCKAP5
Atlas of Cancer Signalling NetworkNCKAP5
Wikipedia pathwaysNCKAP5
Orthology - Evolution
OrthoDB344148
GeneTree (enSembl)ENSG00000176771
Phylogenetic Trees/Animal Genes : TreeFamNCKAP5
HOGENOMO14513
Homologs : HomoloGeneNCKAP5
Homology/Alignments : Family Browser (UCSC)NCKAP5
Gene fusions - Rearrangements
Fusion PortalLYPD1 NCKAP5
Fusion PortalOSMR NCKAP5
Fusion PortalNAALADL2 NCKAP5
Fusion PortalNCKAP5 DYNC2H1
Fusion PortalNCKAP5 MZT2A
Fusion : QuiverNCKAP5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNCKAP5 [hg38]
dbVarNCKAP5
ClinVarNCKAP5
MonarchNCKAP5
1000_GenomesNCKAP5 
Exome Variant ServerNCKAP5
GNOMAD BrowserENSG00000176771
Varsome BrowserNCKAP5
Genomic Variants (DGV)NCKAP5 [DGVbeta]
DECIPHERNCKAP5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNCKAP5 
Mutations
ICGC Data PortalNCKAP5 
TCGA Data PortalNCKAP5 
Broad Tumor PortalNCKAP5
OASIS PortalNCKAP5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNCKAP5  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNCKAP5
Mutations and Diseases : HGMDNCKAP5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NCKAP5
DgiDB (Drug Gene Interaction Database)NCKAP5
DoCM (Curated mutations)NCKAP5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NCKAP5 (select a term)
intoGenNCKAP5
Cancer3DNCKAP5(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608789   
Orphanet
DisGeNETNCKAP5
MedgenNCKAP5
Genetic Testing Registry NCKAP5
NextProtO14513 [Medical]
GENETestsNCKAP5
Target ValidationNCKAP5
Huge Navigator NCKAP5 [HugePedia]
ClinGenNCKAP5
Clinical trials, drugs, therapy
MyCancerGenomeNCKAP5
Protein Interactions : CTD
Pharm GKB GenePA165696957
Clinical trialNCKAP5
Miscellaneous
canSAR (ICR)NCKAP5 (select the gene name)
HarmonizomeNCKAP5
DataMed IndexNCKAP5
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNCKAP5
EVEXNCKAP5
GoPubMedNCKAP5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Dec 5 17:18:48 CET 2020

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.