Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4692
MIM: 602117
HGNC: 7675
Ensembl: ENSG00000182636
Variants:
dbSNP: 4692
ClinVar: 4692
TCGA: ENSG00000182636
COSMIC: NDN
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000182636 | ENST00000649030 | Q99608 |
| ENSG00000182636 | ENST00000649030 | X5D982 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32529326 | 2020 | The necdin interactome: evaluating the effects of amino acid substitutions and cell stress using proximity-dependent biotinylation (BioID) and mass spectrometry. | 3 |
| 32529326 | 2020 | The necdin interactome: evaluating the effects of amino acid substitutions and cell stress using proximity-dependent biotinylation (BioID) and mass spectrometry. | 3 |
| 29343559 | 2018 | A genetic locus for paranoia. | 7 |
| 30102380 | 2018 | Loss of hierarchical imprinting regulation at the Prader-Willi/Angelman syndrome locus in human iPSCs. | 13 |
| 29343559 | 2018 | A genetic locus for paranoia. | 7 |
| 30102380 | 2018 | Loss of hierarchical imprinting regulation at the Prader-Willi/Angelman syndrome locus in human iPSCs. | 13 |
| 28213671 | 2017 | Exome analysis of Smith-Magenis-like syndrome cohort identifies de novo likely pathogenic variants. | 13 |
| 28521288 | 2017 | Hypermethylation of NDN promotes cell proliferation by activating the Wnt signaling pathway in colorectal cancer. | 12 |
| 28213671 | 2017 | Exome analysis of Smith-Magenis-like syndrome cohort identifies de novo likely pathogenic variants. | 13 |
| 28521288 | 2017 | Hypermethylation of NDN promotes cell proliferation by activating the Wnt signaling pathway in colorectal cancer. | 12 |
| 26689988 | 2016 | NDN is an imprinted tumor suppressor gene that is downregulated in ovarian cancers through genetic and epigenetic mechanisms. | 9 |
| 26689988 | 2016 | NDN is an imprinted tumor suppressor gene that is downregulated in ovarian cancers through genetic and epigenetic mechanisms. | 9 |
| 26384308 | 2015 | Necdin is a breast cancer metastasis suppressor that regulates the transcription of c-Myc. | 8 |
| 26518708 | 2015 | NDN and CD1A are novel prognostic methylation markers in patients with head and neck squamous carcinomas. | 15 |
| 26384308 | 2015 | Necdin is a breast cancer metastasis suppressor that regulates the transcription of c-Myc. | 8 |
Citation
Dessen P
NDN (necdin, MAGE family member)
Atlas Genet Cytogenet Oncol Haematol. 2009-11-01
Online version: http://atlasgeneticsoncology.org/gene/51233/ndn
