Atlas of Genetics and Cytogenetics in Oncology and Haematology

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NDUFB6 (NADH:ubiquinone oxidoreductase subunit B6)

Identity

Alias_namesNADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6 (17kD, B17)
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
Alias_symbol (synonym)B17
CI
Other alias
HGNC (Hugo) NDUFB6
LocusID (NCBI) 4712
Atlas_Id 55431
Location 9p21.1  [Link to chromosome band 9p21]
Location_base_pair Starts at 32553526 and ends at 32573184 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TOPORS (9p21.1) / NDUFB6 (9p21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)NDUFB6   7701
Cards
Entrez_Gene (NCBI)NDUFB6  4712  NADH:ubiquinone oxidoreductase subunit B6
AliasesB17; CI
GeneCards (Weizmann)NDUFB6
Ensembl hg19 (Hinxton)ENSG00000165264 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000165264 [Gene_View]  ENSG00000165264 [Sequence]  chr9:32553526-32573184 [Contig_View]  NDUFB6 [Vega]
ICGC DataPortalENSG00000165264
TCGA cBioPortalNDUFB6
AceView (NCBI)NDUFB6
Genatlas (Paris)NDUFB6
WikiGenes4712
SOURCE (Princeton)NDUFB6
Genetics Home Reference (NIH)NDUFB6
Genomic and cartography
GoldenPath hg38 (UCSC)NDUFB6  -     chr9:32553526-32573184 -  9p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NDUFB6  -     9p21.1   [Description]    (hg19-Feb_2009)
GoldenPathNDUFB6 - 9p21.1 [CytoView hg19]  NDUFB6 - 9p21.1 [CytoView hg38]
ImmunoBaseENSG00000165264
Mapping of homologs : NCBINDUFB6 [Mapview hg19]  NDUFB6 [Mapview hg38]
OMIM603322   
Gene and transcription
Genbank (Entrez)AF035840 AF067167 AK092649 AK289702 AW160372
RefSeq transcript (Entrez)NM_001199987 NM_002493 NM_182739
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NDUFB6
Cluster EST : UnigeneHs.493668 [ NCBI ]
CGAP (NCI)Hs.493668
Alternative Splicing GalleryENSG00000165264
Gene ExpressionNDUFB6 [ NCBI-GEO ]   NDUFB6 [ EBI - ARRAY_EXPRESS ]   NDUFB6 [ SEEK ]   NDUFB6 [ MEM ]
Gene Expression Viewer (FireBrowse)NDUFB6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4712
GTEX Portal (Tissue expression)NDUFB6
Human Protein AtlasENSG00000165264-NDUFB6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95139   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95139  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95139
Splice isoforms : SwissVarO95139
PhosPhoSitePlusO95139
Domains : Interpro (EBI)NADH_DH_b-subcmplx_su6   
Domain families : Pfam (Sanger)NDUF_B6 (PF09782)   
Domain families : Pfam (NCBI)pfam09782   
Conserved Domain (NCBI)NDUFB6
DMDM Disease mutations4712
Blocks (Seattle)NDUFB6
PDB (RSDB)5XTC    5XTD    5XTH    5XTI   
PDB Europe5XTC    5XTD    5XTH    5XTI   
PDB (PDBSum)5XTC    5XTD    5XTH    5XTI   
PDB (IMB)5XTC    5XTD    5XTH    5XTI   
Structural Biology KnowledgeBase5XTC    5XTD    5XTH    5XTI   
SCOP (Structural Classification of Proteins)5XTC    5XTD    5XTH    5XTI   
CATH (Classification of proteins structures)5XTC    5XTD    5XTH    5XTI   
SuperfamilyO95139
Human Protein Atlas [tissue]ENSG00000165264-NDUFB6 [tissue]
Peptide AtlasO95139
HPRD04504
IPIIPI00219385   IPI00982696   IPI00375914   
Protein Interaction databases
DIP (DOE-UCLA)O95139
IntAct (EBI)O95139
FunCoupENSG00000165264
BioGRIDNDUFB6
STRING (EMBL)NDUFB6
ZODIACNDUFB6
Ontologies - Pathways
QuickGOO95139
Ontology : AmiGOnucleoplasm  mitochondrion  mitochondrial inner membrane  mitochondrial respiratory chain complex I  mitochondrial respiratory chain complex I  mitochondrial respiratory chain complex I  mitochondrial respiratory chain complex I  mitochondrial electron transport, NADH to ubiquinone  mitochondrial electron transport, NADH to ubiquinone  NADH dehydrogenase (ubiquinone) activity  integral component of membrane  mitochondrial membrane  mitochondrial respiratory chain complex I assembly  mitochondrial respiratory chain complex I assembly  mitochondrial ATP synthesis coupled electron transport  mitochondrial ATP synthesis coupled electron transport  
Ontology : EGO-EBInucleoplasm  mitochondrion  mitochondrial inner membrane  mitochondrial respiratory chain complex I  mitochondrial respiratory chain complex I  mitochondrial respiratory chain complex I  mitochondrial respiratory chain complex I  mitochondrial electron transport, NADH to ubiquinone  mitochondrial electron transport, NADH to ubiquinone  NADH dehydrogenase (ubiquinone) activity  integral component of membrane  mitochondrial membrane  mitochondrial respiratory chain complex I assembly  mitochondrial respiratory chain complex I assembly  mitochondrial ATP synthesis coupled electron transport  mitochondrial ATP synthesis coupled electron transport  
Pathways : KEGGOxidative phosphorylation    Non-alcoholic fatty liver disease (NAFLD)    Alzheimer's disease    Parkinson's disease    Huntington's disease   
NDEx NetworkNDUFB6
Atlas of Cancer Signalling NetworkNDUFB6
Wikipedia pathwaysNDUFB6
Orthology - Evolution
OrthoDB4712
GeneTree (enSembl)ENSG00000165264
Phylogenetic Trees/Animal Genes : TreeFamNDUFB6
HOGENOMO95139
Homologs : HomoloGeneNDUFB6
Homology/Alignments : Family Browser (UCSC)NDUFB6
Gene fusions - Rearrangements
Fusion : QuiverNDUFB6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNDUFB6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NDUFB6
dbVarNDUFB6
ClinVarNDUFB6
1000_GenomesNDUFB6 
Exome Variant ServerNDUFB6
ExAC (Exome Aggregation Consortium)ENSG00000165264
GNOMAD BrowserENSG00000165264
Varsome BrowserNDUFB6
Genetic variants : HAPMAP4712
Genomic Variants (DGV)NDUFB6 [DGVbeta]
DECIPHERNDUFB6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNDUFB6 
Mutations
ICGC Data PortalNDUFB6 
TCGA Data PortalNDUFB6 
Broad Tumor PortalNDUFB6
OASIS PortalNDUFB6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNDUFB6  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNDUFB6
Mutations and Diseases : HGMDNDUFB6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch NDUFB6
DgiDB (Drug Gene Interaction Database)NDUFB6
DoCM (Curated mutations)NDUFB6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NDUFB6 (select a term)
intoGenNDUFB6
Cancer3DNDUFB6(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603322   
Orphanet
DisGeNETNDUFB6
MedgenNDUFB6
Genetic Testing Registry NDUFB6
NextProtO95139 [Medical]
TSGene4712
GENETestsNDUFB6
Target ValidationNDUFB6
Huge Navigator NDUFB6 [HugePedia]
snp3D : Map Gene to Disease4712
BioCentury BCIQNDUFB6
ClinGenNDUFB6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4712
Chemical/Pharm GKB GenePA31512
Clinical trialNDUFB6
Miscellaneous
canSAR (ICR)NDUFB6 (select the gene name)
DataMed IndexNDUFB6
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNDUFB6
EVEXNDUFB6
GoPubMedNDUFB6
iHOPNDUFB6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:57:37 CET 2019
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