| Nomenclature |
|---|
| HGNC (Hugo) | NDUFS6 7713 |
| Cards |
|---|
| Entrez_Gene (NCBI) | NDUFS6 4726 NADH:ubiquinone oxidoreductase subunit S6 |
| Aliases | CI-13kA; CI-13kD-A; CI13KDA; MC1DN9 |
| GeneCards (Weizmann) | NDUFS6 |
| Ensembl hg19 (Hinxton) | ENSG00000145494 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000145494 [Gene_View] ENSG00000145494 [Sequence] chr5:1801382-1816051 [Contig_View] NDUFS6 [Vega] |
| ICGC DataPortal | ENSG00000145494 |
| TCGA cBioPortal | NDUFS6 |
| AceView (NCBI) | NDUFS6 |
| Genatlas (Paris) | NDUFS6 |
| WikiGenes | 4726 |
| SOURCE (Princeton) | NDUFS6 |
| Genetics Home Reference (NIH) | NDUFS6 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | NDUFS6 - chr5:1801382-1816051 + 5p15.33 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | NDUFS6 - 5p15.33 [Description] (hg19-Feb_2009) |
| GoldenPath | NDUFS6 - 5p15.33 [CytoView hg19] NDUFS6 - 5p15.33 [CytoView hg38] |
| ImmunoBase | ENSG00000145494 |
| Mapping of homologs : NCBI | NDUFS6 [Mapview hg19] NDUFS6 [Mapview hg38] |
| OMIM | 603848 618232 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AF044959 AK022503 BC038664 BC046155 BE900424 |
| RefSeq transcript (Entrez) | NM_004553 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | NDUFS6 |
| Alternative Splicing Gallery | ENSG00000145494 |
| Gene Expression | NDUFS6 [ NCBI-GEO ] NDUFS6 [ EBI - ARRAY_EXPRESS ]
NDUFS6 [ SEEK ] NDUFS6 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | NDUFS6 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 4726 |
| GTEX Portal (Tissue expression) | NDUFS6 |
| Human Protein Atlas | ENSG00000145494-NDUFS6 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | O75380 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | O75380 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | O75380 |
| Splice isoforms : SwissVar | O75380 |
| PhosPhoSitePlus | O75380 |
| Domains : Interpro (EBI) | NDUFS6 Znf_CHCC |
| Domain families : Pfam (Sanger) | zf-CHCC (PF10276) |
| Domain families : Pfam (NCBI) | pfam10276 |
| Conserved Domain (NCBI) | NDUFS6 |
| DMDM Disease mutations | 4726 |
| Blocks (Seattle) | NDUFS6 |
| PDB (RSDB) | 5XTB 5XTD 5XTH 5XTI |
| PDB Europe | 5XTB 5XTD 5XTH 5XTI |
| PDB (PDBSum) | 5XTB 5XTD 5XTH 5XTI |
| PDB (IMB) | 5XTB 5XTD 5XTH 5XTI |
| Structural Biology KnowledgeBase | 5XTB 5XTD 5XTH 5XTI |
| SCOP (Structural Classification of Proteins) | 5XTB 5XTD 5XTH 5XTI |
| CATH (Classification of proteins structures) | 5XTB 5XTD 5XTH 5XTI |
| Superfamily | O75380 |
| Human Protein Atlas [tissue] | ENSG00000145494-NDUFS6 [tissue] |
| Peptide Atlas | O75380 |
| HPRD | 10356 |
| IPI | IPI00025344 IPI00965997 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | O75380 |
| IntAct (EBI) | O75380 |
| FunCoup | ENSG00000145494 |
| BioGRID | NDUFS6 |
| STRING (EMBL) | NDUFS6 |
| ZODIAC | NDUFS6 |
| Ontologies - Pathways |
|---|
| QuickGO | O75380 |
| Ontology : AmiGO | mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial respiratory chain complex I mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone mitochondrial electron transport, NADH to ubiquinone mitochondrial electron transport, NADH to ubiquinone fatty acid metabolic process muscle contraction NADH dehydrogenase (ubiquinone) activity electron transfer activity multicellular organism aging mitochondrial respiratory chain complex I assembly multicellular organism growth reproductive system development mitochondrion morphogenesis cardiovascular system development |
| Ontology : EGO-EBI | mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial respiratory chain complex I mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone mitochondrial electron transport, NADH to ubiquinone mitochondrial electron transport, NADH to ubiquinone fatty acid metabolic process muscle contraction NADH dehydrogenase (ubiquinone) activity electron transfer activity multicellular organism aging mitochondrial respiratory chain complex I assembly multicellular organism growth reproductive system development mitochondrion morphogenesis cardiovascular system development |
| Pathways : KEGG | Oxidative phosphorylation Non-alcoholic fatty liver disease (NAFLD) Alzheimer's disease Parkinson's disease Huntington's disease |
| NDEx Network | NDUFS6 |
| Atlas of Cancer Signalling Network | NDUFS6 |
| Wikipedia pathways | NDUFS6 |
| Orthology - Evolution |
|---|
| OrthoDB | 4726 |
| GeneTree (enSembl) | ENSG00000145494 |
| Phylogenetic Trees/Animal Genes : TreeFam | NDUFS6 |
| HOGENOM | O75380 |
| Homologs : HomoloGene | NDUFS6 |
| Homology/Alignments : Family Browser (UCSC) | NDUFS6 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Mitelman | NDUFS6/ACTB [5p15.33/7p22.1] |
| Fusion : Quiver | NDUFS6 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | NDUFS6 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | NDUFS6 |
| dbVar | NDUFS6 |
| ClinVar | NDUFS6 |
| 1000_Genomes | NDUFS6 |
| Exome Variant Server | NDUFS6 |
| ExAC (Exome Aggregation Consortium) | ENSG00000145494 |
| GNOMAD Browser | ENSG00000145494 |
| Varsome Browser | NDUFS6 |
| Genetic variants : HAPMAP | 4726 |
| Genomic Variants (DGV) | NDUFS6 [DGVbeta] |
| DECIPHER | NDUFS6 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | NDUFS6 |
| Mutations |
|---|
| ICGC Data Portal | NDUFS6 |
| TCGA Data Portal | NDUFS6 |
| Broad Tumor Portal | NDUFS6 |
| OASIS Portal | NDUFS6 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | NDUFS6 [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | NDUFS6 |
| Mutations and Diseases : HGMD | NDUFS6 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| LOVD (Leiden Open Variation Database) | MSeqDR-LSDB Mitochondrial Disease Locus Specific Database |
| BioMuta | search NDUFS6 |
| DgiDB (Drug Gene Interaction Database) | NDUFS6 |
| DoCM (Curated mutations) | NDUFS6 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | NDUFS6 (select a term) |
| intoGen | NDUFS6 |
| Cancer3D | NDUFS6(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 603848 618232 |
| Orphanet | 369 |
| DisGeNET | NDUFS6 |
| Medgen | NDUFS6 |
| Genetic Testing Registry | NDUFS6
|
| NextProt | O75380 [Medical] |
| TSGene | 4726 |
| GENETests | NDUFS6 |
| Target Validation | NDUFS6 |
| Huge Navigator |
NDUFS6 [HugePedia] |
| snp3D : Map Gene to Disease | 4726 |
| BioCentury BCIQ | NDUFS6 |
| ClinGen | NDUFS6 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 4726 |
| Chemical/Pharm GKB Gene | PA31523 |
| Clinical trial | NDUFS6 |
| Miscellaneous |
|---|
| canSAR (ICR) | NDUFS6 (select the gene name) |
| Harmonizome | NDUFS6 |
| DataMed Index | NDUFS6 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 36 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | NDUFS6 |
| EVEX | NDUFS6 |
| GoPubMed | NDUFS6 |
| iHOP | NDUFS6 |
