| Nomenclature |
HGNC (Hugo) | NDUFS8 7715 |
| Cards |
Entrez_Gene (NCBI) | NDUFS8 4728 NADH:ubiquinone oxidoreductase core subunit S8 |
Aliases | CI-23k; CI23KD; MC1DN2; TYKY |
GeneCards (Weizmann) | NDUFS8 |
Ensembl hg19 (Hinxton) | ENSG00000110717 [Gene_View] |
Ensembl hg38 (Hinxton) | ENSG00000110717 [Gene_View]  ENSG00000110717 [Sequence] chr11:68030617-68036647 [Contig_View] NDUFS8 [Vega] |
ICGC DataPortal | ENSG00000110717 |
TCGA cBioPortal | NDUFS8 |
AceView (NCBI) | NDUFS8 |
Genatlas (Paris) | NDUFS8 |
WikiGenes | 4728 |
SOURCE (Princeton) | NDUFS8 |
Genetics Home Reference (NIH) | NDUFS8 |
| Genomic and cartography |
GoldenPath hg38 (UCSC) | NDUFS8 - chr11:68030617-68036647 + 11q13.2 [Description] (hg38-Dec_2013) |
GoldenPath hg19 (UCSC) | NDUFS8 - 11q13.2 [Description] (hg19-Feb_2009) |
GoldenPath | NDUFS8 - 11q13.2 [CytoView hg19] NDUFS8 - 11q13.2 [CytoView hg38] |
ImmunoBase | ENSG00000110717 |
Mapping of homologs : NCBI | NDUFS8 [Mapview hg19] NDUFS8 [Mapview hg38] |
OMIM | 602141 618222 |
| Gene and transcription |
Genbank (Entrez) | AK002110 AK223114 AK302449 AK314546 BC119753 |
RefSeq transcript (Entrez) | NM_002496 |
RefSeq genomic (Entrez) | |
Consensus coding sequences : CCDS (NCBI) | NDUFS8 |
Cluster EST : Unigene | Hs.90443 [ NCBI ] |
CGAP (NCI) | Hs.90443 |
Alternative Splicing Gallery | ENSG00000110717 |
Gene Expression | NDUFS8 [ NCBI-GEO ] NDUFS8 [ EBI - ARRAY_EXPRESS ]
NDUFS8 [ SEEK ] NDUFS8 [ MEM ] |
Gene Expression Viewer (FireBrowse) | NDUFS8 [ Firebrowse - Broad ] |
SOURCE (Princeton) | Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60] |
Genevestigator | Expression in : [tissues]  [cell-lines]  [cancer]  [perturbations]   |
BioGPS (Tissue expression) | 4728 |
GTEX Portal (Tissue expression) | NDUFS8 |
Human Protein Atlas | ENSG00000110717-NDUFS8 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
UniProt/SwissProt | O00217 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
NextProt | O00217 [Sequence] [Exons] [Medical] [Publications] |
With graphics : InterPro | O00217 |
Splice isoforms : SwissVar | O00217 |
Catalytic activity : Enzyme | 1.6.5.3 [ Enzyme-Expasy ] 1.6.5.31.6.5.3 [ IntEnz-EBI ] 1.6.5.3 [ BRENDA ] 1.6.5.3 [ KEGG ] |
PhosPhoSitePlus | O00217 |
Domaine pattern : Prosite (Expaxy) | 4FE4S_FER_1 (PS00198) 4FE4S_FER_2 (PS51379) |
Domains : Interpro (EBI) | 4Fe4S_Fe-S-bd 4Fe4S_Fe_S_CS NADH_quinone_OxRdtase_chainI |
Domain families : Pfam (Sanger) | Fer4_7 (PF12838) |
Domain families : Pfam (NCBI) | pfam12838 |
Conserved Domain (NCBI) | NDUFS8 |
DMDM Disease mutations | 4728 |
Blocks (Seattle) | NDUFS8 |
PDB (RSDB) | 5XTB 5XTD 5XTH 5XTI |
PDB Europe | 5XTB 5XTD 5XTH 5XTI |
PDB (PDBSum) | 5XTB 5XTD 5XTH 5XTI |
PDB (IMB) | 5XTB 5XTD 5XTH 5XTI |
Structural Biology KnowledgeBase | 5XTB 5XTD 5XTH 5XTI |
SCOP (Structural Classification of Proteins) | 5XTB 5XTD 5XTH 5XTI |
CATH (Classification of proteins structures) | 5XTB 5XTD 5XTH 5XTI |
Superfamily | O00217 |
Human Protein Atlas [tissue] | ENSG00000110717-NDUFS8 [tissue] |
Peptide Atlas | O00217 |
IPI | IPI00010845 IPI00908766 IPI00977785 IPI00980544 IPI00983992 IPI00982019 IPI00984633 IPI01026455 IPI00977184 IPI00983459 |
| Protein Interaction databases |
DIP (DOE-UCLA) | O00217 |
IntAct (EBI) | O00217 |
FunCoup | ENSG00000110717 |
BioGRID | NDUFS8 |
STRING (EMBL) | NDUFS8 |
ZODIAC | NDUFS8 |
| Ontologies - Pathways |
QuickGO | O00217 |
Ontology : AmiGO | NADH dehydrogenase activity NADH dehydrogenase activity mitochondrion mitochondrial respiratory chain complex I mitochondrial respiratory chain complex I mitochondrial respiratory chain complex I mitochondrial respiratory chain complex I mitochondrial matrix mitochondrial electron transport, NADH to ubiquinone mitochondrial electron transport, NADH to ubiquinone mitochondrial electron transport, NADH to ubiquinone response to oxidative stress NADH dehydrogenase (ubiquinone) activity NADH dehydrogenase (ubiquinone) activity aerobic respiration mitochondrial respiratory chain complex I assembly mitochondrial respiratory chain complex I assembly mitochondrial respiratory chain complex I assembly metal ion binding 4 iron, 4 sulfur cluster binding |
Ontology : EGO-EBI | NADH dehydrogenase activity NADH dehydrogenase activity mitochondrion mitochondrial respiratory chain complex I mitochondrial respiratory chain complex I mitochondrial respiratory chain complex I mitochondrial respiratory chain complex I mitochondrial matrix mitochondrial electron transport, NADH to ubiquinone mitochondrial electron transport, NADH to ubiquinone mitochondrial electron transport, NADH to ubiquinone response to oxidative stress NADH dehydrogenase (ubiquinone) activity NADH dehydrogenase (ubiquinone) activity aerobic respiration mitochondrial respiratory chain complex I assembly mitochondrial respiratory chain complex I assembly mitochondrial respiratory chain complex I assembly metal ion binding 4 iron, 4 sulfur cluster binding |
Pathways : KEGG | Oxidative phosphorylation Non-alcoholic fatty liver disease (NAFLD) Alzheimer's disease Parkinson's disease Huntington's disease |
NDEx Network | NDUFS8 |
Atlas of Cancer Signalling Network | NDUFS8 |
Wikipedia pathways | NDUFS8 |
| Orthology - Evolution |
OrthoDB | 4728 |
GeneTree (enSembl) | ENSG00000110717 |
Phylogenetic Trees/Animal Genes : TreeFam | NDUFS8 |
HOGENOM | O00217 |
Homologs : HomoloGene | NDUFS8 |
Homology/Alignments : Family Browser (UCSC) | NDUFS8 |
| Gene fusions - Rearrangements |
Fusion : Quiver | NDUFS8 |
| Polymorphisms : SNP and Copy number variants |
NCBI Variation Viewer | NDUFS8 [hg38] |
dbSNP Single Nucleotide Polymorphism (NCBI) | NDUFS8 |
dbVar | NDUFS8 |
ClinVar | NDUFS8 |
1000_Genomes | NDUFS8 |
Exome Variant Server | NDUFS8 |
ExAC (Exome Aggregation Consortium) | ENSG00000110717 |
GNOMAD Browser | ENSG00000110717 |
Varsome Browser | NDUFS8 |
Genetic variants : HAPMAP | 4728 |
Genomic Variants (DGV) | NDUFS8 [DGVbeta] |
DECIPHER | NDUFS8 [patients] [syndromes] [variants] [genes] |
CONAN: Copy Number Analysis | NDUFS8 |
| Mutations |
ICGC Data Portal | NDUFS8 |
TCGA Data Portal | NDUFS8 |
Broad Tumor Portal | NDUFS8 |
OASIS Portal | NDUFS8 [ Somatic mutations - Copy number] |
Somatic Mutations in Cancer : COSMIC | NDUFS8 [overview] [genome browser] [tissue] [distribution] |
Somatic Mutations in Cancer : COSMIC3D | NDUFS8 |
Mutations and Diseases : HGMD | NDUFS8 |
BioMuta | search NDUFS8 |
DgiDB (Drug Gene Interaction Database) | NDUFS8 |
DoCM (Curated mutations) | NDUFS8 (select the gene name) |
CIViC (Clinical Interpretations of Variants in Cancer) | NDUFS8 (select a term) |
intoGen | NDUFS8 |
Cancer3D | NDUFS8(select the gene name) |
Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
---|
OMIM | 602141 618222 |
Orphanet | |
DisGeNET | NDUFS8 |
Medgen | NDUFS8 |
Genetic Testing Registry | NDUFS8
|
NextProt | O00217 [Medical] |
TSGene | 4728 |
GENETests | NDUFS8 |
Target Validation | NDUFS8 |
Huge Navigator |
NDUFS8 [HugePedia] |
snp3D : Map Gene to Disease | 4728 |
BioCentury BCIQ | NDUFS8 |
ClinGen | NDUFS8 |
| Clinical trials, drugs, therapy |
---|
Chemical/Protein Interactions : CTD | 4728 |
Chemical/Pharm GKB Gene | PA31525 |
Clinical trial | NDUFS8 |
| Miscellaneous |
---|
canSAR (ICR) | NDUFS8 (select the gene name) |
DataMed Index | NDUFS8 |
| Probes |
---|
| Litterature |
---|
PubMed | 47 Pubmed reference(s) in Entrez |
GeneRIFs | Gene References Into Functions (Entrez) |
CoreMine | NDUFS8 |
EVEX | NDUFS8 |
GoPubMed | NDUFS8 |
iHOP | NDUFS8 |