NEAT1 (nuclear paraspeckle assembly transcript 1)

2014-08-01  

Identity

HGNC
NEAT1
LOCATION
11q13.1
LOCUSID
283131
ALIAS
LINC00084,NCRNA00084,TncRNA,VINC
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 283131
MIM: 612769
HGNC: 30815
Ensembl: ENSG00000245532

Variants:

dbSNP: 283131
ClinVar: 283131
TCGA: ENSG00000245532
COSMIC: NEAT1

RNA/Proteins

Expression (GTEx)

0
100
200
300
400
500
600
700
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
245077152014Long noncoding RNA NEAT1-dependent SFPQ relocation from promoter region to paraspeckle mediates IL8 expression upon immune stimuli.207
254152302014The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer.131
229606382012Alternative 3'-end processing of long noncoding RNA initiates construction of nuclear paraspeckles.117
273511352016Long non-coding RNA NEAT1 promotes non-small cell lung cancer progression through regulation of miR-377-3p-E2F3 pathway.104
254177002015Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival.72
268227632016Long noncoding RNA NEAT1 promotes laryngeal squamous cell cancer through regulating miR-107/CDK6 pathway.71
215323452011LSINCT5 is over expressed in breast and ovarian cancer and affects cellular proliferation.58
270205922016The long non-coding RNA NEAT1 regulates epithelial to mesenchymal transition and radioresistance in through miR-204/ZEB1 axis in nasopharyngeal carcinoma.55
262422662016Long noncoding RNA NEAT1 promotes glioma pathogenesis by regulating miR-449b-5p/c-Met axis.52
287127282017HEXIM1 and NEAT1 Long Non-coding RNA Form a Multi-subunit Complex that Regulates DNA-Mediated Innate Immune Response.49

Citation

Dessen P

NEAT1 (nuclear paraspeckle assembly transcript 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54497/neat1