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NECAB1 (N-terminal EF-hand calcium binding protein 1)

Identity

Alias_namesEFCBP1
EF-hand calcium binding protein 1
Other aliasSTIP-1
HGNC (Hugo) NECAB1
LocusID (NCBI) 64168
Atlas_Id 70792
Location 8q21.3  [Link to chromosome band 8q21]
Location_base_pair Starts at 90791693 and ends at 90959402 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
VPS13B (8q22.2) / NECAB1 (8q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)NECAB1   20983
Cards
Entrez_Gene (NCBI)NECAB1  64168  N-terminal EF-hand calcium binding protein 1
AliasesEFCBP1; STIP-1
GeneCards (Weizmann)NECAB1
Ensembl hg19 (Hinxton)ENSG00000123119 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000123119 [Gene_View]  ENSG00000123119 [Sequence]  chr8:90791693-90959402 [Contig_View]  NECAB1 [Vega]
ICGC DataPortalENSG00000123119
TCGA cBioPortalNECAB1
AceView (NCBI)NECAB1
Genatlas (Paris)NECAB1
WikiGenes64168
SOURCE (Princeton)NECAB1
Genetics Home Reference (NIH)NECAB1
Genomic and cartography
GoldenPath hg38 (UCSC)NECAB1  -     chr8:90791693-90959402 +  8q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NECAB1  -     8q21.3   [Description]    (hg19-Feb_2009)
GoldenPathNECAB1 - 8q21.3 [CytoView hg19]  NECAB1 - 8q21.3 [CytoView hg38]
ImmunoBaseENSG00000123119
Mapping of homologs : NCBINECAB1 [Mapview hg19]  NECAB1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF193756 AF414126 AK095533 AK098356 AY224210
RefSeq transcript (Entrez)NM_022351
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NECAB1
Cluster EST : UnigeneHs.719466 [ NCBI ]
CGAP (NCI)Hs.719466
Alternative Splicing GalleryENSG00000123119
Gene ExpressionNECAB1 [ NCBI-GEO ]   NECAB1 [ EBI - ARRAY_EXPRESS ]   NECAB1 [ SEEK ]   NECAB1 [ MEM ]
Gene Expression Viewer (FireBrowse)NECAB1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64168
GTEX Portal (Tissue expression)NECAB1
Human Protein AtlasENSG00000123119-NECAB1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N987   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N987  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N987
Splice isoforms : SwissVarQ8N987
PhosPhoSitePlusQ8N987
Domaine pattern : Prosite (Expaxy)ABM (PS51725)    EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)   
Domains : Interpro (EBI)ABM_dom    Dimeric_a/b-barrel    EF-hand-dom_pair    EF_Hand_1_Ca_BS    EF_hand_dom   
Domain families : Pfam (Sanger)ABM (PF03992)    EF-hand_8 (PF13833)   
Domain families : Pfam (NCBI)pfam03992    pfam13833   
Domain families : Smart (EMBL)EFh (SM00054)  
Conserved Domain (NCBI)NECAB1
DMDM Disease mutations64168
Blocks (Seattle)NECAB1
SuperfamilyQ8N987
Human Protein Atlas [tissue]ENSG00000123119-NECAB1 [tissue]
Peptide AtlasQ8N987
HPRD16851
IPIIPI00171206   IPI00843940   
Protein Interaction databases
DIP (DOE-UCLA)Q8N987
IntAct (EBI)Q8N987
FunCoupENSG00000123119
BioGRIDNECAB1
STRING (EMBL)NECAB1
ZODIACNECAB1
Ontologies - Pathways
QuickGOQ8N987
Ontology : AmiGOblastocyst hatching  molecular_function  calcium ion binding  nucleus  nucleoplasm  cytoplasm  cytoplasm  cytosol  biological_process  regulation of amyloid precursor protein biosynthetic process  
Ontology : EGO-EBIblastocyst hatching  molecular_function  calcium ion binding  nucleus  nucleoplasm  cytoplasm  cytoplasm  cytosol  biological_process  regulation of amyloid precursor protein biosynthetic process  
NDEx NetworkNECAB1
Atlas of Cancer Signalling NetworkNECAB1
Wikipedia pathwaysNECAB1
Orthology - Evolution
OrthoDB64168
GeneTree (enSembl)ENSG00000123119
Phylogenetic Trees/Animal Genes : TreeFamNECAB1
HOGENOMQ8N987
Homologs : HomoloGeneNECAB1
Homology/Alignments : Family Browser (UCSC)NECAB1
Gene fusions - Rearrangements
Fusion : QuiverNECAB1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNECAB1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NECAB1
dbVarNECAB1
ClinVarNECAB1
1000_GenomesNECAB1 
Exome Variant ServerNECAB1
ExAC (Exome Aggregation Consortium)ENSG00000123119
GNOMAD BrowserENSG00000123119
Varsome BrowserNECAB1
Genetic variants : HAPMAP64168
Genomic Variants (DGV)NECAB1 [DGVbeta]
DECIPHERNECAB1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNECAB1 
Mutations
ICGC Data PortalNECAB1 
TCGA Data PortalNECAB1 
Broad Tumor PortalNECAB1
OASIS PortalNECAB1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNECAB1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNECAB1
Mutations and Diseases : HGMDNECAB1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NECAB1
DgiDB (Drug Gene Interaction Database)NECAB1
DoCM (Curated mutations)NECAB1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NECAB1 (select a term)
intoGenNECAB1
Cancer3DNECAB1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETNECAB1
MedgenNECAB1
Genetic Testing Registry NECAB1
NextProtQ8N987 [Medical]
TSGene64168
GENETestsNECAB1
Target ValidationNECAB1
Huge Navigator NECAB1 [HugePedia]
snp3D : Map Gene to Disease64168
BioCentury BCIQNECAB1
ClinGenNECAB1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64168
Chemical/Pharm GKB GenePA162397411
Clinical trialNECAB1
Miscellaneous
canSAR (ICR)NECAB1 (select the gene name)
DataMed IndexNECAB1
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNECAB1
EVEXNECAB1
GoPubMedNECAB1
iHOPNECAB1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Sep 3 15:57:39 CEST 2019
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