NECAP2 (NECAP endocytosis associated 2)

2003-05-01  

Identity

HGNC
NECAP2
LOCATION
1p36.13
LOCUSID
55707
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55707
MIM: 611624
HGNC: 25528
Ensembl: ENSG00000157191

Variants:

dbSNP: 55707
ClinVar: 55707
TCGA: ENSG00000157191
COSMIC: NECAP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000157191ENST00000337132Q9NVZ3
ENSG00000157191ENST00000337132A0A024QZ81
ENSG00000157191ENST00000443980Q9NVZ3
ENSG00000157191ENST00000457722Q9NVZ3
ENSG00000157191ENST00000459640F6SKB8
ENSG00000157191ENST00000492095Q9NVZ3
ENSG00000157191ENST00000492095A0A024QZ81
ENSG00000157191ENST00000504551D6RB24
ENSG00000157191ENST00000504858D6RAN6
ENSG00000157191ENST00000513161H0Y970

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Clathrin-mediated endocytosisREACTOMER-HSA-8856828
Cargo recognition for clathrin-mediated endocytosisREACTOMER-HSA-8856825

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
145559622003Identification of a family of endocytic proteins that define a new alpha-adaptin ear-binding motif.27
272068612016NECAP2 controls clathrin coat recruitment to early endosomes for fast endocytic recycling.10

Citation

Dessen P

NECAP2 (NECAP endocytosis associated 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/40583/necap2