Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4738
MIM: 603171
HGNC: 7732
Ensembl: ENSG00000129559
Variants:
dbSNP: 4738
ClinVar: 4738
TCGA: ENSG00000129559
COSMIC: NEDD8
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000129559 | ENST00000250495 | Q15843 |
| ENSG00000129559 | ENST00000396828 | F8VSA6 |
| ENSG00000129559 | ENST00000524927 | F8VSA6 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38391033 | 2024 | Advancements in colorectal cancer research: Unveiling the cellular and molecular mechanisms of neddylation (Review). | 0 |
| 38678024 | 2024 | Loss of NEDD8 in cancer cells causes vulnerability to immune checkpoint blockade in triple-negative breast cancer. | 0 |
| 38391033 | 2024 | Advancements in colorectal cancer research: Unveiling the cellular and molecular mechanisms of neddylation (Review). | 0 |
| 38678024 | 2024 | Loss of NEDD8 in cancer cells causes vulnerability to immune checkpoint blockade in triple-negative breast cancer. | 0 |
| 37905484 | 2023 | [Differential expression of NEDD8 in different pathological types of chronic rhinosinusitis with nasal polyps]. | 0 |
| 37905484 | 2023 | [Differential expression of NEDD8 in different pathological types of chronic rhinosinusitis with nasal polyps]. | 0 |
| 34716866 | 2022 | Blocking neddylation elicits antiviral effect against hepatitis B virus replication. | 2 |
| 34716866 | 2022 | Blocking neddylation elicits antiviral effect against hepatitis B virus replication. | 2 |
| 33268465 | 2021 | The Mechanism of NEDD8 Activation of CUL5 Ubiquitin E3 Ligases. | 9 |
| 33288957 | 2021 | Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler. | 18 |
| 33420360 | 2021 | TAS4464, a NEDD8-activating enzyme inhibitor, activates both intrinsic and extrinsic apoptotic pathways via c-Myc-mediated regulation in acute myeloid leukemia. | 15 |
| 33472076 | 2021 | Proteome-wide identification of NEDD8 modification sites reveals distinct proteomes for canonical and atypical NEDDylation. | 28 |
| 33966047 | 2021 | Map of ubiquitin-like post-translational modifications in chronic lymphocytic leukemia. Role of p53 lysine 120 NEDDylation. | 2 |
| 34156462 | 2021 | The HSP70 chaperone as sensor of the NEDD8 cycle upon DNA damage. | 1 |
| 34642328 | 2021 | Structural and functional consequences of NEDD8 phosphorylation. | 9 |
Citation
Dessen P
NEDD8 (NEDD8 ubiquitin like modifier)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/41518/nedd8
