NEK5 (NIMA related kinase 5)

2006-10-01  

Identity

HGNC
NEK5
LOCATION
13q14.3
LOCUSID
341676
ALIAS
-

Other Information

Locus ID:

NCBI: 341676
MIM: 616731
HGNC: 7748
Ensembl: ENSG00000197168

Variants:

dbSNP: 341676
ClinVar: 341676
TCGA: ENSG00000197168
COSMIC: NEK5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197168ENST00000355568Q6P3R8
ENSG00000197168ENST00000465811E9PIX7
ENSG00000197168ENST00000617045Q6P3R8
ENSG00000197168ENST00000647945A0A3B3ITQ6
ENSG00000197168ENST00000652119A0A494C168

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
306759232019NEK5 promotes breast cancer cell proliferation through up-regulation of Cyclin A2.3
319068782020Expression of the NEK family in normal and cancer tissue: an immunohistochemical study.2
257252882015Nek5 interacts with mitochondrial proteins and interferes negatively in mitochondrial mediated cell death and respiration.0
259638172015Nek5 promotes centrosome integrity in interphase and loss of centrosome cohesion in mitosis.0

Citation

Dessen P

NEK5 (NIMA related kinase 5)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43373/nek5