Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7469
MIM: 606026
HGNC: 12768
Ensembl: ENSG00000185049
Variants:
dbSNP: 7469
ClinVar: 7469
TCGA: ENSG00000185049
COSMIC: NELFA
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36463234 | 2022 | ERK-mediated NELF-A phosphorylation promotes transcription elongation of immediate-early genes by releasing promoter-proximal pausing of RNA polymerase II. | 4 |
| 36463234 | 2022 | ERK-mediated NELF-A phosphorylation promotes transcription elongation of immediate-early genes by releasing promoter-proximal pausing of RNA polymerase II. | 4 |
| 33548202 | 2021 | Stress-induced nuclear condensation of NELF drives transcriptional downregulation. | 50 |
| 33548202 | 2021 | Stress-induced nuclear condensation of NELF drives transcriptional downregulation. | 50 |
| 31845510 | 2020 | The noncoding function of NELFA mRNA promotes the development of oesophageal squamous cell carcinoma by regulating the Rad17-RFC2-5 complex. | 2 |
| 31845510 | 2020 | The noncoding function of NELFA mRNA promotes the development of oesophageal squamous cell carcinoma by regulating the Rad17-RFC2-5 complex. | 2 |
| 27282391 | 2016 | Architecture and RNA binding of the human negative elongation factor. | 38 |
| 27282391 | 2016 | Architecture and RNA binding of the human negative elongation factor. | 38 |
| 24097989 | 2013 | A conserved protein motif is required for full modulatory activity of negative elongation factor subunits NELF-A and NELF-B in modifying glucocorticoid receptor-regulated gene induction properties. | 9 |
| 24097989 | 2013 | A conserved protein motif is required for full modulatory activity of negative elongation factor subunits NELF-A and NELF-B in modifying glucocorticoid receptor-regulated gene induction properties. | 9 |
| 22328085 | 2012 | Characterizing the functional consequences of haploinsufficiency of NELF-A (WHSC2) and SLBP identifies novel cellular phenotypes in Wolf-Hirschhorn syndrome. | 22 |
| 22328085 | 2012 | Characterizing the functional consequences of haploinsufficiency of NELF-A (WHSC2) and SLBP identifies novel cellular phenotypes in Wolf-Hirschhorn syndrome. | 22 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 19245807 | 2009 | Cellular dynamics of the negative transcription elongation factor NELF. | 4 |
Citation
Dessen P
NELFA (negative elongation factor complex member A)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/42811/nelfa
