Atlas of Genetics and Cytogenetics in Oncology and Haematology

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NEO1 (neogenin 1)

Identity

Alias_namesneogenin (chicken) homolog 1
Alias_symbol (synonym)NGN
HsT17534
IGDCC2
NTN1R2
Other alias
HGNC (Hugo) NEO1
LocusID (NCBI) 4756
Atlas_Id 41525
Location 15q24.1  [Link to chromosome band 15q24]
Location_base_pair Starts at 73052484 and ends at 73305206 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NEO1 (15q24.1) / NEO1 (15q24.1)SIN3A (15q24.2) / NEO1 (15q24.1)ZNF324 (19q13.43) / NEO1 (15q24.1)
SIN3A 15q24.2 / NEO1 15q24.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  SIN3A/NEO1 (15q24)

External links

Nomenclature
HGNC (Hugo)NEO1   7754
Cards
Entrez_Gene (NCBI)NEO1  4756  neogenin 1
AliasesIGDCC2; NGN; NTN1R2
GeneCards (Weizmann)NEO1
Ensembl hg19 (Hinxton)ENSG00000067141 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000067141 [Gene_View]  ENSG00000067141 [Sequence]  chr15:73052484-73305206 [Contig_View]  NEO1 [Vega]
ICGC DataPortalENSG00000067141
TCGA cBioPortalNEO1
AceView (NCBI)NEO1
Genatlas (Paris)NEO1
WikiGenes4756
SOURCE (Princeton)NEO1
Genetics Home Reference (NIH)NEO1
Genomic and cartography
GoldenPath hg38 (UCSC)NEO1  -     chr15:73052484-73305206 +  15q24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NEO1  -     15q24.1   [Description]    (hg19-Feb_2009)
GoldenPathNEO1 - 15q24.1 [CytoView hg19]  NEO1 - 15q24.1 [CytoView hg38]
ImmunoBaseENSG00000067141
Mapping of homologs : NCBINEO1 [Mapview hg19]  NEO1 [Mapview hg38]
OMIM601907   
Gene and transcription
Genbank (Entrez)AB209412 AL355708 AL359597 AL390182 BC117161
RefSeq transcript (Entrez)NM_001172623 NM_001172624 NM_002499
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NEO1
Cluster EST : UnigeneHs.388613 [ NCBI ]
CGAP (NCI)Hs.388613
Alternative Splicing GalleryENSG00000067141
Gene ExpressionNEO1 [ NCBI-GEO ]   NEO1 [ EBI - ARRAY_EXPRESS ]   NEO1 [ SEEK ]   NEO1 [ MEM ]
Gene Expression Viewer (FireBrowse)NEO1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4756
GTEX Portal (Tissue expression)NEO1
Human Protein AtlasENSG00000067141-NEO1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92859   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92859  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92859
Splice isoforms : SwissVarQ92859
PhosPhoSitePlusQ92859
Domaine pattern : Prosite (Expaxy)FN3 (PS50853)    IG_LIKE (PS50835)   
Domains : Interpro (EBI)FN3_dom    FN3_sf    Ig-like_dom    Ig-like_dom_sf    Ig-like_fold    Ig_I-set    Ig_sub    Ig_sub2    Neogenin    Neogenin_C   
Domain families : Pfam (Sanger)fn3 (PF00041)    I-set (PF07679)    Ig_2 (PF13895)    Neogenin_C (PF06583)   
Domain families : Pfam (NCBI)pfam00041    pfam07679    pfam13895    pfam06583   
Domain families : Smart (EMBL)FN3 (SM00060)  IG (SM00409)  IGc2 (SM00408)  
Conserved Domain (NCBI)NEO1
DMDM Disease mutations4756
Blocks (Seattle)NEO1
PDB (RSDB)1X5F    1X5G    1X5H    1X5I    1X5J    1X5K    3P4L   
PDB Europe1X5F    1X5G    1X5H    1X5I    1X5J    1X5K    3P4L   
PDB (PDBSum)1X5F    1X5G    1X5H    1X5I    1X5J    1X5K    3P4L   
PDB (IMB)1X5F    1X5G    1X5H    1X5I    1X5J    1X5K    3P4L   
Structural Biology KnowledgeBase1X5F    1X5G    1X5H    1X5I    1X5J    1X5K    3P4L   
SCOP (Structural Classification of Proteins)1X5F    1X5G    1X5H    1X5I    1X5J    1X5K    3P4L   
CATH (Classification of proteins structures)1X5F    1X5G    1X5H    1X5I    1X5J    1X5K    3P4L   
SuperfamilyQ92859
Human Protein Atlas [tissue]ENSG00000067141-NEO1 [tissue]
Peptide AtlasQ92859
HPRD03549
IPIIPI00023814   IPI00217291   IPI00472011   IPI00556554   
Protein Interaction databases
DIP (DOE-UCLA)Q92859
IntAct (EBI)Q92859
FunCoupENSG00000067141
BioGRIDNEO1
STRING (EMBL)NEO1
ZODIACNEO1
Ontologies - Pathways
QuickGOQ92859
Ontology : AmiGOprotein binding  nucleoplasm  Golgi apparatus  plasma membrane  plasma membrane  integral component of plasma membrane  cell adhesion  axon guidance  positive regulation of BMP signaling pathway  signaling receptor activity  co-receptor binding  iron ion homeostasis  plasma membrane protein complex  
Ontology : EGO-EBIprotein binding  nucleoplasm  Golgi apparatus  plasma membrane  plasma membrane  integral component of plasma membrane  cell adhesion  axon guidance  positive regulation of BMP signaling pathway  signaling receptor activity  co-receptor binding  iron ion homeostasis  plasma membrane protein complex  
Pathways : KEGGCell adhesion molecules (CAMs)   
NDEx NetworkNEO1
Atlas of Cancer Signalling NetworkNEO1
Wikipedia pathwaysNEO1
Orthology - Evolution
OrthoDB4756
GeneTree (enSembl)ENSG00000067141
Phylogenetic Trees/Animal Genes : TreeFamNEO1
HOGENOMQ92859
Homologs : HomoloGeneNEO1
Homology/Alignments : Family Browser (UCSC)NEO1
Gene fusions - Rearrangements
Fusion : MitelmanSIN3A/NEO1 [15q24.2/15q24.1]  [t(15;15)(q24;q24)]  
Fusion PortalSIN3A 15q24.2 NEO1 15q24.1 BRCA
Fusion : QuiverNEO1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNEO1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NEO1
dbVarNEO1
ClinVarNEO1
1000_GenomesNEO1 
Exome Variant ServerNEO1
ExAC (Exome Aggregation Consortium)ENSG00000067141
GNOMAD BrowserENSG00000067141
Varsome BrowserNEO1
Genetic variants : HAPMAP4756
Genomic Variants (DGV)NEO1 [DGVbeta]
DECIPHERNEO1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNEO1 
Mutations
ICGC Data PortalNEO1 
TCGA Data PortalNEO1 
Broad Tumor PortalNEO1
OASIS PortalNEO1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNEO1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNEO1
Mutations and Diseases : HGMDNEO1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NEO1
DgiDB (Drug Gene Interaction Database)NEO1
DoCM (Curated mutations)NEO1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NEO1 (select a term)
intoGenNEO1
Cancer3DNEO1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601907   
Orphanet
DisGeNETNEO1
MedgenNEO1
Genetic Testing Registry NEO1
NextProtQ92859 [Medical]
TSGene4756
GENETestsNEO1
Target ValidationNEO1
Huge Navigator NEO1 [HugePedia]
snp3D : Map Gene to Disease4756
BioCentury BCIQNEO1
ClinGenNEO1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4756
Chemical/Pharm GKB GenePA31555
Clinical trialNEO1
Miscellaneous
canSAR (ICR)NEO1 (select the gene name)
DataMed IndexNEO1
Probes
Litterature
PubMed54 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNEO1
EVEXNEO1
GoPubMedNEO1
iHOPNEO1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 13 17:57:48 CET 2019
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