NEUROG1 (neurogenin 1)

2011-08-01 Affiliation

Identity

HGNC

NEUROG1

LOCATION

5q31.1

LOCUSID

4762

ALIAS

AKA,Math4C,NEUROD3,bHLHa6,ngn1

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 4762
MIM: 601726
HGNC: 7764
Ensembl: ENSG00000181965

Variants:

dbSNP: 4762
ClinVar: 4762
TCGA: ENSG00000181965
COSMIC: NEUROG1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000181965	ENST00000314744	Q92886
ENSG00000181965	ENST00000314744	F1T0H3

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Signaling pathways regulating pluripotency of stem cells	KEGG	hsa04550
Signaling pathways regulating pluripotency of stem cells	KEGG	ko04550

References

Pubmed ID	Year	Title	Citations
25403753	2014	Rapid neurogenesis through transcriptional activation in human stem cells.	59
21326223	2011	Methylation of NEUROG1 in serum is a sensitive marker for the detection of early colorectal cancer.	42
19086053	2009	Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.	34
23034738	2013	Methylation and microsatellite status and recurrence following adjuvant FOLFOX in colorectal cancer.	22
18053270	2007	Association of autism with polymorphisms in the paired-like homeodomain transcription factor 1 (PITX1) on chromosome 5q31: a candidate gene analysis.	13
20102160	2010	The basic helix-loop-helix region of human neurogenin 1 is a monomeric natively unfolded protein which forms a "fuzzy" complex upon DNA binding.	13
17044100	2007	Association between the 5q31.1 gene neurogenin1 and schizophrenia.	8
17044100	2007	Association between the 5q31.1 gene neurogenin1 and schizophrenia.	8
19813087	2010	Stable expression of neurogenin 1 induces LGR5, a novel stem cell marker, in an immortalized human neural stem cell line HB1.F3.	5
23419067	2013	A boy with homozygous microdeletion of NEUROG1 presents with a congenital cranial dysinnervation disorder [Moebius syndrome variant].	3

Citation

Dessen P

NEUROG1 (neurogenin 1)

Atlas Genet Cytogenet Oncol Haematol. 2011-08-01

Online version: http://atlasgeneticsoncology.org/gene/52332/neurog1