Identity
HGNC
LOCATION
16q22.1
LOCUSID
ALIAS
NF-AT5,NFATL1,NFATZ,OREBP,TONEBP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10725
MIM: 604708
HGNC: 7774
Ensembl: ENSG00000102908
Variants:
dbSNP: 10725
ClinVar: 10725
TCGA: ENSG00000102908
COSMIC: NFAT5
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA444552 | Hypertension | Disease | Literature, MultilinkAnnotation | associated | 24560520 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38338716 | 2024 | TonEBP: A Key Transcription Factor in Microglia Following Intracerebral Hemorrhage Induced-Neuroinflammation. | 0 |
| 38438872 | 2024 | TonEBP/NFAT5 expression is associated with cisplatin resistance and migration in macrophage-induced A549 cells. | 0 |
| 38612478 | 2024 | Rel Family Transcription Factor NFAT5 Upregulates COX2 via HIF-1α Activity in Ishikawa and HEC1a Cells. | 0 |
| 38724321 | 2024 | Differentiation and immunosuppressive function of CD19(+)CD24(hi)CD27(+) regulatory B cells are regulated through the miR-29a-3p/NFAT5 pathway. | 0 |
| 38338716 | 2024 | TonEBP: A Key Transcription Factor in Microglia Following Intracerebral Hemorrhage Induced-Neuroinflammation. | 0 |
| 38438872 | 2024 | TonEBP/NFAT5 expression is associated with cisplatin resistance and migration in macrophage-induced A549 cells. | 0 |
| 38612478 | 2024 | Rel Family Transcription Factor NFAT5 Upregulates COX2 via HIF-1α Activity in Ishikawa and HEC1a Cells. | 0 |
| 38724321 | 2024 | Differentiation and immunosuppressive function of CD19(+)CD24(hi)CD27(+) regulatory B cells are regulated through the miR-29a-3p/NFAT5 pathway. | 0 |
| 36652182 | 2023 | SAFB2 Inhibits the Progression of Breast Cancer by Suppressing the Wnt/β-Catenin Signaling Pathway via NFAT5. | 1 |
| 38188678 | 2023 | TonEBP expression is essential in the IL-1β-induced migration and invasion of human A549 lung cancer cells. | 0 |
| 36652182 | 2023 | SAFB2 Inhibits the Progression of Breast Cancer by Suppressing the Wnt/β-Catenin Signaling Pathway via NFAT5. | 1 |
| 38188678 | 2023 | TonEBP expression is essential in the IL-1β-induced migration and invasion of human A549 lung cancer cells. | 0 |
| 35417913 | 2022 | Associations of the Methylation Levels of NFAT5, PVT1, RPS6KA1, and MIB1 with Steroid-Resistant Asthma. | 0 |
| 35417913 | 2022 | Associations of the Methylation Levels of NFAT5, PVT1, RPS6KA1, and MIB1 with Steroid-Resistant Asthma. | 0 |
| 32828883 | 2021 | Up-Regulation of Nfat5 mRNA and Fzd4 mRNA as a Marker of Poor Outcome in Neonatal Hypoxic-Ischemic Encephalopathy. | 2 |
Citation
Dessen P
NFAT5 (nuclear factor of activated T cells 5)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43657/nfat5
