Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4778
MIM: 601490
HGNC: 7780
Ensembl: ENSG00000123405
Variants:
dbSNP: 4778
ClinVar: 4778
TCGA: ENSG00000123405
COSMIC: NFE2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Hemostasis | REACTOME | R-HSA-109582 |
| Factors involved in megakaryocyte development and platelet production | REACTOME | R-HSA-983231 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33945619 | 2021 | Impact of NFE2 mutations on AML transformation and overall survival in patients with myeloproliferative neoplasms. | 14 |
| 34559205 | 2021 | In a multi-institutional cohort of myeloid sarcomas, NFE2 mutation prevalence is lower than previously reported. | 0 |
| 33945619 | 2021 | Impact of NFE2 mutations on AML transformation and overall survival in patients with myeloproliferative neoplasms. | 14 |
| 34559205 | 2021 | In a multi-institutional cohort of myeloid sarcomas, NFE2 mutation prevalence is lower than previously reported. | 0 |
| 31659782 | 2020 | Characteristics and clinical correlates of NFE2 mutations in chronic Myeloproliferative neoplasms. | 5 |
| 32593231 | 2020 | Nuclear factor erythroid 2 (NF-E2) p45-related factor 2 interferes with homeodomain-interacting protein kinase 2/p53 activity to impair solid tumors chemosensitivity. | 7 |
| 32593672 | 2020 | The transcription factor NFE2 enhances expression of the hematopoietic master regulators SCL/TAL1 and GATA2. | 3 |
| 31659782 | 2020 | Characteristics and clinical correlates of NFE2 mutations in chronic Myeloproliferative neoplasms. | 5 |
| 32593231 | 2020 | Nuclear factor erythroid 2 (NF-E2) p45-related factor 2 interferes with homeodomain-interacting protein kinase 2/p53 activity to impair solid tumors chemosensitivity. | 7 |
| 32593672 | 2020 | The transcription factor NFE2 enhances expression of the hematopoietic master regulators SCL/TAL1 and GATA2. | 3 |
| 30755419 | 2019 | Altered NFE2 activity predisposes to leukemic transformation and myelosarcoma with AML-specific aberrations. | 14 |
| 31455213 | 2019 | NFE2/miR-423-5p/TFF1 axis regulates high glucose-induced apoptosis in retinal pigment epithelial cells. | 15 |
| 30755419 | 2019 | Altered NFE2 activity predisposes to leukemic transformation and myelosarcoma with AML-specific aberrations. | 14 |
| 31455213 | 2019 | NFE2/miR-423-5p/TFF1 axis regulates high glucose-induced apoptosis in retinal pigment epithelial cells. | 15 |
| 29476075 | 2018 | The cytoprotective role of DJ-1 and p45 NFE2 against human primary alveolar type II cell injury and emphysema. | 11 |
Citation
Dessen P
NFE2 (nuclear factor, erythroid 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41529/nfe2
